Immature B cell homing shapes human lymphoid tissue structure and function.
| Autor: | Spencer J; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK., Dionisi C; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, UK. |
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| Jazyk: | angličtina |
| Zdroj: | The Journal of experimental medicine [J Exp Med] 2024 Sep 02; Vol. 221 (9). Date of Electronic Publication: 2024 Aug 02. |
| DOI: | 10.1084/jem.20240085 |
| Abstrakt: | Shortly after the emergence of newly formed human B cells from bone marrow as transitional cells, they diverge along two developmental pathways that can be distinguished by the level of IgM they express and migratory biases. Here, we propose that differential tissue homing of immature B cell subsets contributes to human lymphoid tissue structure and function. (© 2024 Spencer and Dionisi.) |
| Databáze: | MEDLINE |
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