The association between conditioned pain modulation and psychological factors in people with chronic spinal pain: A systematic review.

Autor:	Mansfield M; School of Sport, Exercise and Rehabilitation Sciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK.; Centre of Precision Rehabilitation for Spinal Pain, University of Birmingham, Birmingham, UK.; Faculty of Medicine and Health Sciences, University of East Anglia, Norwich, UK., Roviello G; School of Sport, Exercise and Rehabilitation Sciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK.; Physiotherapy Department, Guy's and St Thomas' Hospitals NHS Foundation Trust, London, UK., Thacker M; School of Physiotherapy, Royal College of Surgeons Ireland, Dublin, Ireland., Willett M; School of Sport, Exercise and Rehabilitation Sciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK.; Centre of Precision Rehabilitation for Spinal Pain, University of Birmingham, Birmingham, UK., Bannister K; Central Modulation of Pain, Wolfson Centre of Age Related Diseases, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Smith T; Warwick Medical School, University of Warwick, Coventry, UK.
Jazyk:	angličtina
Zdroj:	British journal of pain [Br J Pain] 2024 Aug; Vol. 18 (4), pp. 314-324. Date of Electronic Publication: 2024 Jan 24.
DOI:	10.1177/20494637241229970
Abstrakt:	Chronic spinal pain has negative effects on physical and mental well-being. Psychological factors can influence pain tolerance. However, whether these factors influence descending modulatory control mechanisms measured by conditioned pain modulation (CPM) in people with chronic spinal pain is unclear. This systematic review investigated the association between CPM response and psychological factors in people with chronic spinal pain. Published and unpublished literature databases were searched from inception to 23rd October 2023 included MEDLINE, EMBASE, CINAHL, and PubMed. Studies assessing the association between CPM response and psychological factors in people with chronic spinal pain were eligible. Data were pooled through meta-analysis. Methodological quality was assessed using the AXIS tool and the certainty of evidence measured through GRADE. From 2172 records, seven studies ( n = 598) were eligible. Quality of included studies was moderate. There was very low certainty of evidence that depression ( r = 0.01 [95% CI -0.10 to 0.12], I 2 = 0%), and anxiety ( r = -0.20 [95% CI -0.56 to 0.16], I 2 = 84%), fear avoidance ( r = -0.10 [95% CI -0.30 to 0.10], I 2 = 70%) had no statistical associations with CPM responder status. Higher pain catastrophising was associated with CPM non-responder status (r = -0.19; 95% CI: -0.37 to -0.02; n = 545; I2: 76%) based on a very low certainty of evidence measured by GRADE. There is currently limited available evidence demonstrating an association between CPM response and psychological factors for people with chronic pain. Managing an individual's chronic pain symptoms irrespective of comorbid psychological distress, should continue until evidence offer insights that more targeted interventions are needed. Competing Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. (© The Author(s) 2024.)
Databáze:	MEDLINE
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