The role of arousal in maintaining the relationship between insomnia and gastrointestinal conditions.

Autor:	Rameshkumar S; Rogers Behavioral Health, Hinsdale, IL, USA., Arizmendi BJ; Department of Psychiatry and Psychology, Mayo Clinic Arizona, Scottsdale, AZ, USA., Salwen-Deremer JK; Department of Psychiatry & Center for Digestive Health, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.
Jazyk:	angličtina
Zdroj:	Translational gastroenterology and hepatology [Transl Gastroenterol Hepatol] 2024 Jul 09; Vol. 9, pp. 41. Date of Electronic Publication: 2024 Jul 09 (Print Publication: 2024).
DOI:	10.21037/tgh-23-126
Abstrakt:	The relationship between gastrointestinal (GI) conditions and sleep disturbance has been well established. With a higher-than-average prevalence of sleep disturbance in individuals with GI conditions, it is imperative to better understand the maintaining factors driving this comorbidity. Although there are separate, ongoing investigations into both the biological mechanisms and interventions for the sleep and GI relationship, there is a considerable need to further specify common and mutually influential pathways. In our review, we highlight arousal as both a unifying feature of insomnia and various GI conditions as well as a possible mechanism for action for the bidirectional relationship. This review aims to summarize the relationship between arousal, insomnia, and GI conditions, specifically examining sources of arousal across four broad domains: psychosocial factors, physical health factors, daily living factors, and sociocultural factors. Online databases, including PubMed, PsychInfo, and Google Scholar, were searched for full-text English language articles focused on patients with insomnia and/or GI conditions and involving mental health, physical comorbidities, and social factors. Understanding the nature of this bidirectional relationship between sleep and GI through the lens of arousal as a common mechanism will lend itself to using a multidisciplinary approach to treatment and care. Competing Interests: Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://tgh.amegroups.com/article/view/10.21037/tgh-23-126/coif). The series “Social and Emotional Impacts of Chronic Digestive Diseases” was commissioned by the editorial office without any funding or sponsorship. J.K.S.D. reports that this work was supported by the National Institute of Diabetes and Digestive and Kidney Diseases (No. K23DK134814) and reports grant from Crohn’s & Colitis Foundation Litwin IBD Pioneers Award, honoraria from Crohn’s & Colitis Foundation, ROME Foundation and Johns Hopkins University and research support through supplies from Buhlmann Diagnostics. Honoraria do not pertain directly to the manuscript’s content. The authors have no other conflicts of interest to declare. (2024 Translational Gastroenterology and Hepatology. All rights reserved.)
Databáze:	MEDLINE
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