Synchronous cemento-ossifying fibromas: a systematic review.

Autor: Neumann BL; Universidade Federal do Rio Grande do Sul Faculdade de Odontologia, Rua Ramiro Barcelos, 2492, sala 503 CEP: 90035-003, Santana, Porto Alegre RS, Brazil manomartins@gmail.com., Mendes EM, Só BB, Silveira FM, Wagner VP, Vargas PA, Santos JN, Fonseca FP, Bologna-Molina RE, Mosqueda-Taylor A, Martins MA, Martins MD
Jazyk: angličtina
Zdroj: Medicina oral, patologia oral y cirugia bucal [Med Oral Patol Oral Cir Bucal] 2024 Sep 01; Vol. 29 (5), pp. e591-e597. Date of Electronic Publication: 2024 Sep 01.
DOI: 10.4317/medoral.26501
Abstrakt: Background: This systematic review aimed to incorporate published data regarding synchronous cemento-ossifying fibromas (COF), with an analysis of their demographic and clinicopathological characteristics.
Material and Methods: Case reports and case series of synchronous COF were searched in PubMed, Web of Science, Scopus, EMBASE, and LILACS according to the PRISMA (2020) statement. Also, a manual search was carried out and the grey literature was assessed. A descriptive statistical analysis was performed.
Results: Nineteen studies comprising 20 cases of synchronous COF were included. The mean age at diagnosis was 35 years (±13.8), with a predominance of female patients (n=12/60%). In 13 cases (65%) the mandible and the maxilla were affected simultaneously. In two cases (10%) first-degree relatives (parents or siblings) had been previously diagnosed with COF. The diagnostic hypotheses were reported in 8 cases (40%), with florid cemento-osseous dysplasia, ameloblastic fibroodontoma, calcifying cystic odontogenic tumor, osteoma and cementoblastoma being cited in the differential diagnosis. Among the cases with details about management (n=17), eleven were treated by surgical enucleation and/or excision (64.7%). Follow-up was provided for 10 cases (50%), with a mean period of 44.7±62.19 months. Recurrence occurred in three of informed cases.
Conclusions: Synchronous manifestation of COF is rare. Female patients around the 3rd decade of life are more commonly affected. Bilateral involvement of the mandible and maxilla is the most common clinical presentation.
Databáze: MEDLINE