Knowledge of Tuberculosis preventive treatment among people living with HIV: A cross-sectional survey in selected regions of Tanzania.

Autor: Alexander FC; National Institute for Medical Research-Muhimbili Center, Dar es Salaam, Tanzania., Mshiu JJ; National Institute for Medical Research-Muhimbili Center, Dar es Salaam, Tanzania., Rushaigo AM; National Institute for Medical Research-Muhimbili Center, Dar es Salaam, Tanzania., Mgina EJ; National Institute for Medical Research headquarter, Dar es Salaam, Tanzania., Wiketye VE; National Institute for Medical Research-Ngongongare Station, Arusha, Tanzania., Mtundi SC; National Institute for Medical Research-Muhimbili Center, Dar es Salaam, Tanzania., Haule ST; National Institute for Medical Research-Muhimbili Center, Dar es Salaam, Tanzania., Katende MK; National Institute for Medical Research-Muhimbili Center, Dar es Salaam, Tanzania., Evarist EM; National Institute for Medical Research-Muhimbili Center, Dar es Salaam, Tanzania., Kapama LC; National Institute for Medical Research-Muhimbili Center, Dar es Salaam, Tanzania., Shemdoe AI; National Institute for Medical Research-Muhimbili Center, Dar es Salaam, Tanzania., Makasi CE; National Institute for Medical Research-Muhimbili Center, Dar es Salaam, Tanzania., Lolakeha MM; National Institute for Medical Research-Muhimbili Center, Dar es Salaam, Tanzania., Minja VK; National Institute for Medical Research-Muhimbili Center, Dar es Salaam, Tanzania., Kimbute OA; National Institute for Medical Research-Muhimbili Center, Dar es Salaam, Tanzania., Stephen KJ; National Institute for Medical Research-Muhimbili Center, Dar es Salaam, Tanzania., Range NS; National Institute for Medical Research-Muhimbili Center, Dar es Salaam, Tanzania., Maokola WM; National AIDS Control Program (NACP) (Now known as National AIDS, STIs and Hepatitis Control Program (NASHCoP), Dodoma, Tanzania., Ngowi BJ; National Institute for Medical Research-Muhimbili Center, Dar es Salaam, Tanzania., Nyigo VA; National Institute for Medical Research-Muhimbili Center, Dar es Salaam, Tanzania., Kilale AM; National Institute for Medical Research-Muhimbili Center, Dar es Salaam, Tanzania.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2024 Aug 01; Vol. 19 (8), pp. e0307670. Date of Electronic Publication: 2024 Aug 01 (Print Publication: 2024).
DOI: 10.1371/journal.pone.0307670
Abstrakt: Background: Tuberculosis remains a significant global health concern, especially for People Living with HIV, who are at an increased risk of severe TB disease. Despite the availability of TB Preventive Treatment, knowledge gaps persist among People Living with HIV regarding its importance, accessibility, and administration. The study aimed to assess TPT knowledge levels and determinants among People Living with HIV in Tanzania.
Methods: A cross-sectional survey was conducted from April to May 2023 in 12 regions of mainland Tanzania. The study included PLHIV aged 18 years and above, receiving HIV care in selected Care and Treatment Centers. Data were collected through face-to-face interviews using a semi-structured questionnaire covering sociodemographic characteristics and Tuberculosis preventive treatment knowledge. Descriptive statistics, chi-square tests, and logistic regression analyses were employed for data analysis.
Results: Out of the 391 People Living with HIV interviewed, 71.4% demonstrated adequate Tuberculosis preventive treatment knowledge. Female participants, those attending urban health facilities, and individuals with longer durations of HIV care exhibited higher Tuberculosis preventive treatment knowledge levels. However, knowledge disparities persisted based on demographic characteristics such as gender and location of health facilities.
Conclusion: While a considerable portion of People Living with HIV demonstrated adequate higher Tuberculosis preventive treatment knowledge, addressing gaps among those with lower understanding is crucial. Targeted education campaigns tailored to the needs of People Living with HIV, especially in rural areas and among male populations, are essential. Collaborative efforts between national health programs and community organizations are vital to integrate Tuberculosis preventive treatment awareness effectively into comprehensive HIV care programs, ultimately reducing the burden of Tuberculosis among People Living with HIV and the general population.
Competing Interests: The authors have declared that no competing interests exist
(Copyright: © 2024 Alexander et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze: MEDLINE
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