Nicotine Toxicity From Repeat Use of Nicotine Pouches.

Autor:	Kent JT; Division of Emergency Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada., Mok G; Division of Emergency Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.; Department of Emergency Medicine, St. Michael's Hospital, Toronto, Ontario, Canada., Austin E; Division of Emergency Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.; Department of Emergency Medicine, St. Michael's Hospital, Toronto, Ontario, Canada.; Ontario Poison Centre, Toronto, Ontario, Canada.
Jazyk:	angličtina
Zdroj:	Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco [Nicotine Tob Res] 2024 Aug 01. Date of Electronic Publication: 2024 Aug 01.
DOI:	10.1093/ntr/ntae111
Abstrakt:	Background: Nicotine pouches have emerged as a novel way to administer concentrated nicotine and come as a white powder in flavored, microfiber pouches placed between the cheek and gums to dissolve without requiring spitting. While marketed as a safe alternative to smoking, nicotine pouches have the potential for toxic exposure to users. Case Presentation: We present a case of a 21-year-old male with acute nicotine toxicity through repeated administration of nicotine pouches. Over the course of 12 hours, he consumed 15 extra-strength nicotine pouches (10.9 mg per pouch) as a study tool to prepare for the next-day exams. He presented to the emergency department with bizarre behavior requiring admission for persistent confusion and nausea which resolved after 24 hours. Conclusions: This case represents the first case of acute nicotine toxicity secondary to nicotine pouch use. These pouches are emerging as a novel way to use nicotine and present a serious risk of inadvertent overdose and harm. Implications: Nicotine pouches are emerging as a novel way to use nicotine, and second to e-cigarettes, are the most frequently used nicotine product among youth. These pouches, which lack clear warning labels, are promoted among social media forums and present a serious risk of inadvertent overdose and harm, especially among young adults. Healthcare professionals should be aware of this risk, especially from acute, repeated exposures, and should ensure the public is cautioned appropriately. (© The Author(s) 2024. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco.)
Databáze:	MEDLINE
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