Limited Evidence to Support the Use of Intra-Articular Injection of Hyaluronic Acid for the Management of Hallux Rigidus: A Systematic Review.

Autor:	Butler JJ; Foot and Ankle Division, Department of Orthopaedic Surgery, NYU Langone Health, New York City, USA., Hartman H; LMU-DeBusk College of Osteopathic Medicine, Knoxville, TN, USA., Mener A; Albany Medical Center, New York, USA., Mercer NP; Foot and Ankle Division, Department of Orthopaedic Surgery, NYU Langone Health, New York City, USA., Randall GW; Foot and Ankle Division, Department of Orthopaedic Surgery, NYU Langone Health, New York City, USA., Petropoulos S; Royal College of Surgeons in Ireland, Dublin, Ireland., Rosenbaum AJ; Albany Medical Center, New York, USA., Kennedy JG; Foot and Ankle Division, Department of Orthopaedic Surgery, NYU Langone Health, New York City, USA.
Jazyk:	angličtina
Zdroj:	Foot & ankle orthopaedics [Foot Ankle Orthop] 2024 Jul 29; Vol. 9 (3), pp. 24730114241265109. Date of Electronic Publication: 2024 Jul 29 (Print Publication: 2024).
DOI:	10.1177/24730114241265109
Abstrakt:	Background: The purpose of this systematic review was to evaluate outcomes following intra-articular injection of hyaluronic acid (HA) for the treatment of hallux rigidus. Methods: During April 2024, a systematic review of the MEDLINE, EMBASE, and Cochrane Library databases was performed based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Data collected and analyzed were number of patients, patient age, follow-up, subjective clinical outcomes, complications, and failures. Results: Five studies were included. In total, 218 patients (218 feet) underwent intra-articular injection of HA at a weighted mean follow-up time of 4.4 ± 1.4 months (range, 3-6). There was an improvement in postinjection visual analog scale (VAS) pain at rest scores, VAS pain during activity scores, American Orthopaedic Foot & Ankle Society (AOFAS) scores, and Foot Health Status Questionnaire (FHSQ) scores. In total, 21 complications (10.0%) were observed, the most common of which was transient postinjection pain in 20 patients (9.6%). There were 7 patients (3.2%) who underwent secondary procedures (3.2%). One randomized control trial (RCT) demonstrated no difference in outcomes between an intra-articular injection of HA compared to an intra-articular injection of saline. One RCT demonstrated superior FHSQ scores following between an intra-articular injection of HA compared to an intra-articular injection of triamcinolone acetonide. Conclusion: This systematic review suggests that intra-articular injection of HA for the treatment of hallux rigidus may lead to improved clinical outcomes with a low complication rate at short-term follow-up. However, the low level and quality of evidence underscores the need for further high-quality studies to be conducted to identify the precise role of HA in the treatment of hallux rigidus. Competing Interests: The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: John G. Kennedy, MD, MCh, MMSc, FFSEM, FRCS(Orth), is a consultant for In2Bones and Arthrex and receives financial support from the Ohnell Family Foundation, Tatiana Rybak, and Mr Winston Fisher. Disclosure forms for all authors are available online. (© The Author(s) 2024.)
Databáze:	MEDLINE
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