| Autor: |
Nagashima T; Division of Rheumatology, First Department of Comprehensive Medicine, Jichi Medical University Saitama Medical Center, Japan., Yabe H; Division of Rheumatology, First Department of Comprehensive Medicine, Jichi Medical University Saitama Medical Center, Japan., Okabe N; Department of Pathology, Jichi Medical University Saitama Medical Center, Japan., Kobashigawa T; Division of Rheumatology, First Department of Comprehensive Medicine, Jichi Medical University Saitama Medical Center, Japan. |
| Jazyk: |
angličtina |
| Zdroj: |
Internal medicine (Tokyo, Japan) [Intern Med] 2024 Aug 01. Date of Electronic Publication: 2024 Aug 01. |
| DOI: |
10.2169/internalmedicine.3769-24 |
| Abstrakt: |
A 76-year-old woman with persistent diarrhea was referred to our hospital. She had purpura, peripheral eosinophilia (18,177/μL), and an elevated serum IgG4 level (819 mg/dL). Abdominal computed tomography revealed massive ascites and bowel edema. A skin biopsy of the purpura revealed leukocytoclastic vasculitis with prominent eosinophilic infiltration. Biopsies of the gastrointestinal mucosa revealed dense eosinophilic infiltration, indicating eosinophilic gastroenteritis (EG) associated with the hypereosinophilic syndrome. The number of IgG4-positive cells increased in the duodenal mucosa; however, the diagnostic criteria for IgG4-related disease (IgG4-RD) were not met. Whether or not EG with ascites is a manifestation of IgG4-RD warrants further investigation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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