Effects of a mixed additive based on Saccharomyces cerevisiae and Lactobacillus rhamnosus on broilers exposed to aflatoxin B 1 by contaminated feed.

Autor: Fochesato AS; Departamento de Microbiología e Inmunología, Universidad Nacional de Río Cuarto, Ruta 36, km 601, (5800) Río Cuarto, Córdoba, Argentina; Fellow of Council Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Godoy Cruz 2290, Buenos Aires, Argentina., Martínez MP; Departamento de Microbiología e Inmunología, Universidad Nacional de Río Cuarto, Ruta 36, km 601, (5800) Río Cuarto, Córdoba, Argentina; Fellow of Council Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Godoy Cruz 2290, Buenos Aires, Argentina., Cuello D; Departamento de Microbiología e Inmunología, Universidad Nacional de Río Cuarto, Ruta 36, km 601, (5800) Río Cuarto, Córdoba, Argentina., Poloni VL; Departamento de Microbiología e Inmunología, Universidad Nacional de Río Cuarto, Ruta 36, km 601, (5800) Río Cuarto, Córdoba, Argentina; Fellow of Council Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Godoy Cruz 2290, Buenos Aires, Argentina., Luna MJ; Fellow of Council Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Godoy Cruz 2290, Buenos Aires, Argentina; Member of Council Nacional de Investigaciones Científicas y Técnicas (CONICET), Godoy Cruz 2290, Buenos Aires, Argentina., Magnoli AP; Member of Council Nacional de Investigaciones Científicas y Técnicas (CONICET), Godoy Cruz 2290, Buenos Aires, Argentina; Departamento de Producción Animal, Cátedra de Nutrición Animal, Facultad de Agronomía y Veterinaria, Universidad Nacional de Río Cuarto, Córdoba, Argentina., Fernández C; Departamento de Producción Animal, Cátedra de Nutrición Animal, Facultad de Agronomía y Veterinaria, Universidad Nacional de Río Cuarto, Córdoba, Argentina., Cavaglieri LR; Departamento de Microbiología e Inmunología, Universidad Nacional de Río Cuarto, Ruta 36, km 601, (5800) Río Cuarto, Córdoba, Argentina; Member of Council Nacional de Investigaciones Científicas y Técnicas (CONICET), Godoy Cruz 2290, Buenos Aires, Argentina. Electronic address: lcavaglieri@exa.unrc.edu.ar.
Jazyk: angličtina
Zdroj: Revista Argentina de microbiologia [Rev Argent Microbiol] 2024 Jul-Sep; Vol. 56 (3), pp. 312-321. Date of Electronic Publication: 2024 Jul 30.
DOI: 10.1016/j.ram.2023.11.006
Abstrakt: The objective of the present study was to explore the influence of dietary supplementation with a mixed additive (MA) containing a probiotic and anti-mycotoxin (Saccharomyces cerevisiae RC016 and Lactobacillus rhamnosus RC007) and its interaction on the performance and health (biochemistry and liver/intestine histopathology) of broilers fed diets contaminated with aflatoxin B 1 (AFB 1 ) at 506000±22.1ng/kg. The MA contained S. cerevisiae RC016 (1×10 7 cells/g) and L. rhamnosus RC007 (1×10 8 cells/g) in relation 1:1. A total of sixty-one-day-old Cobb broilers were randomly allocated into four treatment groups with three replicates of 5 birds each for a five-week-old feeding experiment. The experimental diet for each treatment (T) was formulated as follows: T1, a commercial diet (CD); T2, CD+AFB 1 ; T3, CD+0.1% MA; T4, CD+AFB 1 +0.1% MA. The MA improved (p<0.01) production parameters (weight gain, conversion rate, and carcass yield) and reduced (p<0.01) the toxic effect of AFB 1 on the relative weight of the livers. In addition, the macro and microscopic alterations of livers and the possible intestinal injury related to histological damage in the presence of mycotoxin were reduced. The use of probiotic MA based on S. cerevisiae RC016 and L. rhamnosus RC007 in animal feed provides greater protection against mycotoxin contamination and is safe for use as a supplement in animal feed, providing beneficial effects that improve animal health and productivity. This is of great importance at the economic level for the avian production system.
(Copyright © 2024 Asociación Argentina de Microbiología. Publicado por Elsevier España, S.L.U. All rights reserved.)
Databáze: MEDLINE