Effect of a physical exercise program supported by wearable technology in children with drug-resistant epilepsy. A randomized controlled trial.

Autor: Ibañez-Micó S; Pediatric Neurology Unit, Virgen de la Arrixaca University Clinic Hospital, Murcia, Spain., Gil-Aparicio R; Altabix Health Center, Elche, Alicante, Spain., Gómez-Conesa A; Research Group Research Methods and Evaluation in Social Sciences, Mare Nostrum Campus of International Excellence, University of Murcia, Murcia 30100, Spain. Electronic address: agomez@um.es.
Jazyk: angličtina
Zdroj: Seizure [Seizure] 2024 Oct; Vol. 121, pp. 56-63. Date of Electronic Publication: 2024 Jul 26.
DOI: 10.1016/j.seizure.2024.07.019
Abstrakt: Purpose: to investigate the effects of a physical exercise (PE) program, supported by wearable technology (WT), in children with drug-resistant epilepsy (DRE).
Methods: 29 children with DRE were randomized to experimental (EG) and control (CG) groups. To encourage PE, the EG performed one hour of aerobic activity three days a week for six months, outside the school setting. Compliance was monitored using activity wristbands, with data reported weekly by parents. Health-related quality of life (HRQoL), seizure frequency, physical activity (PA), physical fitness (musculoskeletal, motor, and Cardiorespiratory Fitness), and body composition, were assessed at baseline, at three and six months.
Results: Seizure frequency in the last six months evolved from 10.5 seizures/week at baseline, to 4.5 at the end of the study in the EG, and from 5.2 seizures/week to one in the CG. Significant differences were found in weekly hours-PE (η2= 0.49); motor fitness (η2= 0.08); Cardiorespiratory Fitness (η2= 0.19); weight (η2= 0.003); Triceps skinfold thickness (η2= 0.05); lower limb muscular strength (η2= 0.03); HRQoL (η2= 0.02); and PA (η2= 0.22). Post-hoc ANOVA revealed that EG improved significantly (p < 0.05) between baseline and six months. Negative correlations were observed between PA and seizure frequency.
Conclusion: Supported by WT, children with DRE increased the weekly hours of PE at three and six months, with no increase in seizure frequency. Our study provides evidence of the effectiveness of PE for improving HRQoL.
Competing Interests: Declaration of competing interest None.
(Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: