Exposure to ambient ozone and sperm quality among adult men in China.

Autor: Shi Y; School of Public Health, Capital Medical University, Beijing 100069, China., Zhang Y; School of Public Health, Capital Medical University, Beijing 100069, China., Yuan K; School of Public Health, Capital Medical University, Beijing 100069, China., Han Z; School of Public Health, Capital Medical University, Beijing 100069, China., Zhao S; School of Public Health, Tianjin Medical University, Tianjin 300070, China., Zhang Z; Department of Global Health, Peking University School of Public Health, Beijing, China; Institute for Global Health and Development, Peking University, Beijing 100191, China., Cao W; Department of Social Medicine and Health Education, School of Public Health, Peking University, Beijing 100191, China., Li Y; Reproductive Medicine Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue, Wuhan, Hubei 1095, China. Electronic address: yufengli64@tjh.tjmu.edu.cn., Zeng Q; Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. Electronic address: zengqiang506@hust.edu.cn., Sun S; School of Public Health, Capital Medical University, Beijing 100069, China; Beijing Municipal Key Laboratory of Clinical Epidemiology, Capital Medical University, Beijing 100069, China. Electronic address: shengzhisun@ccmu.edu.cn.
Jazyk: angličtina
Zdroj: Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2024 Sep 15; Vol. 283, pp. 116753. Date of Electronic Publication: 2024 Jul 30.
DOI: 10.1016/j.ecoenv.2024.116753
Abstrakt: Background: Limited evidence exists regarding the association between ozone exposure and adverse sperm quality. We aimed to assess the association between ozone exposure and sperm quality, and identify susceptible exposure windows.
Methods: We recruited 32,541 men aged between 22 and 65 years old attending an infertility clinic in Wuhan, Hubei Province, China from 2014 to 2020. Ozone data were obtained from a satellite-based spatiotemporal model. Generalized linear models were used to estimate the association between ozone exposure and sperm quality parameters, including sperm concentration, sperm count, sperm total motility, and sperm progressive motility during the entire stage of sperm development (0-90 days before ejaculation) and three crucial stages (0-9 days, 10-14 days and 70-90 days before ejaculation). Stratified analyses were performed to evaluate whether associations varied by age, body mass index, and education levels.
Results: The final analysis included 27,854 adult men. A 10 μg/m 3 increase in ozone concentrations during the entire stage of sperm development was associated with a -4.17 % (95 % CI: -4.78 %, -3.57 %) decrease in sperm concentration, -6.54 % (95 % CI: -8.03 %, -5.60 %) decrease in sperm count, -0.50 % (95 % CI: -0.66 %, -0.34 %) decrease in sperm total motility, and -0.07 % (95 % CI: -0.22 %, 0.09 %) decrease in sperm progressive motility. The associations were stronger during 70-90 days before ejaculation and among men with middle school and lower education for sperm concentration.
Conclusions: Ozone exposure was associated with decreased sperm quality among Chinese adult men attending an infertility clinic. These results suggest that ozone may be a risk factor contributing to decreased sperm quality in Chinese men.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024. Published by Elsevier Inc.)
Databáze: MEDLINE
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