Multilayered epigenetic control of persistent and stage-specific imprinted genes in rice endosperm.

Autor: Tonosaki K; Kihara Institute for Biological Research, Yokohama City University, Yokohama, Kanagawa, Japan. tonosaki@yokohama-cu.ac.jp.; Faculty of Agriculture, Iwate University, Morioka, Iwate, Japan. tonosaki@yokohama-cu.ac.jp., Susaki D; Kihara Institute for Biological Research, Yokohama City University, Yokohama, Kanagawa, Japan., Morinaka H; RIKEN Center for Sustainable Resource Science, Yokohama, Kanagawa, Japan., Ono A; Kihara Institute for Biological Research, Yokohama City University, Yokohama, Kanagawa, Japan., Nagata H; Kihara Institute for Biological Research, Yokohama City University, Yokohama, Kanagawa, Japan., Furuumi H; Genetic Strains Research Center, National Institute of Genetics, Mishima, Shizuoka, Japan., Nonomura KI; Plant Cytogenetics, National Institute of Genetics, Mishima, Shizuoka, Japan., Sato Y; Genetic Strains Research Center, National Institute of Genetics, Mishima, Shizuoka, Japan., Sugimoto K; RIKEN Center for Sustainable Resource Science, Yokohama, Kanagawa, Japan., Comai L; Department of Plant Biology and Genome Center, University of California, Davis, CA, USA., Hatakeyama K; Faculty of Agriculture, Iwate University, Morioka, Iwate, Japan., Kawakatsu T; Institute of Agrobiological Sciences, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, Japan. riverwin@naro.affrc.go.jp., Kinoshita T; Kihara Institute for Biological Research, Yokohama City University, Yokohama, Kanagawa, Japan. tkinoshi@yokohama-cu.ac.jp.
Jazyk: angličtina
Zdroj: Nature plants [Nat Plants] 2024 Aug; Vol. 10 (8), pp. 1231-1245. Date of Electronic Publication: 2024 Jul 30.
DOI: 10.1038/s41477-024-01754-4
Abstrakt: In angiosperms, epigenetic profiles for genomic imprinting are established before fertilization. However, the causal relationships between epigenetic modifications and imprinted expression are not fully understood. In this study, we classified 'persistent' and 'stage-specific' imprinted genes on the basis of time-course transcriptome analysis in rice (Oryza sativa) endosperm and compared them to epigenetic modifications at a single time point. While the levels of epigenetic modifications are relatively low in stage-specific imprinted genes, they are considerably higher in persistent imprinted genes. Overall trends revealed that the maternal alleles of maternally expressed imprinted genes are activated by DNA demethylation, while the maternal alleles of paternally expressed imprinted genes with gene body methylation (gbM) are silenced by DNA demethylation and H3K27me3 deposition, and these regions are associated with an enriched motif related to Tc/Mar-Stowaway. Our findings provide insight into the stability of genomic imprinting and the potential variations associated with endosperm development, different cell types and parental genotypes.
(© 2024. The Author(s), under exclusive licence to Springer Nature Limited.)
Databáze: MEDLINE
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