Cutaneous T-cell Lymphoma.
| Autor: | Weiner DM; Department of Dermatology, Johns Hopkins University School of Medicine, 601 North Caroline Street, 8th Floor, Baltimore, MD 21287, USA. Electronic address: dweine13@jh.edu., Rook AH; Department of Dermatology, Cutaneous Lymphoma Program, Perelman School of Medicine, University of Pennsylvania, 3400 Civic Center Boulevard, 1st Floor, Philadelphia, PA 19104, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Hematology/oncology clinics of North America [Hematol Oncol Clin North Am] 2024 Oct; Vol. 38 (5), pp. 1087-1110. Date of Electronic Publication: 2024 Jul 29. |
| DOI: | 10.1016/j.hoc.2024.05.012 |
| Abstrakt: | Cutaneous T-cell lymphoma is a group of non-Hodgkin T-cell lymphomas that develop in and affect the skin but can potentially spread to other organs. There are many subtypes, the most common of which are mycosis fungoides, Sezary syndrome, lymphomatoid papulosis, and primary cutaneous anaplastic large cell lymphoma. Cutaneous lymphoma is a common cause of recalcitrant chronic skin rash and notoriously mimics other dermatologic and hematologic conditions, often resulting in diagnostic delays of months to years. This review provides an introduction to cutaneous T-cell lymphoma, with a primary focus on the clinical presentation, diagnosis, immunopathogenesis, and management of the condition. Competing Interests: Disclosure A.H. Rook is a consultant for TLR Biosciences and speaker for Mallinckrodt. D. M. Weiner has no disclosures. (Copyright © 2024 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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