DXA-derived abdominal fat-free mass to predict MRI skeletal muscle mass in postmenopausal women.

Autor:	Walker E; Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, USA., Chalke AM; Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, USA., Bland VL; School of Nutritional Sciences and Wellness, University of Arizona, Tucson, AZ, USA., Lind KE; Department of Health Promotion Sciences, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, USA., Chen Z; Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, USA., Blew RM; Department of Health Promotion Sciences, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, USA., Odegaard AO; Department of Epidemiology and Biostatistics, University of California, Irvine, CA, USA., Thomson CA; Department of Health Promotion Sciences, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, USA., Caan B; Kaiser Permanente Division of Research, Oakland, CA, USA., Nicholas JS; College of Pharmacy, University of Arizona, Tucson, AZ, USA., Valencia CI; Department of Family and Community Medicine, University of Arizona College of Medicine-Tucson, AZ, USA., Roe DJ; Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, USA., Allison M; Family Medicine and Public Health, University of California, San Diego, CA, USA., Schnatz PF; Department of Obstetrics and Gynecology, Drexel University College of Medicine, Philadelphia, PA, USA., Wactawski-Wende J; School of Public Health and Health Professions, University at Buffalo, SUNY, Buffalo, NY, USA., Bea J; Department of Health Promotion Sciences, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, USA.
Jazyk:	angličtina
Zdroj:	Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme [Appl Physiol Nutr Metab] 2024 Nov 01; Vol. 49 (11), pp. 1606-1610. Date of Electronic Publication: 2024 Jul 30.
DOI:	10.1139/apnm-2024-0046
Abstrakt:	Dual-energy X-ray absorptiometry (DXA) is more available than gold-standard magnetic resonance imaging (MRI), but DXA ability to estimate abdominal skeletal muscle mass (SMM) is unknown. DXA-derived abdominal fat-free mass (FFM; Hologic QDR2000 or QDR4500w) was correlated with single-slice MRI SMM at L4 ( N  = 69; r QDR2000 = 0.71, QDR4500w = 0.69; p  < 0.0001). Linear regression to predict SMM, including DXA FFM, BMI, and age, resulted in an R-squared of 0.72 and 0.65 for QDR2000 and QDR4500. Bland-Altman limits of agreement were ±21 and ±31 g for 2-3 standard deviations from the mean difference. DXA predicted abdominal SSM is a moderate proxy for MRI abdominal SMM. Competing Interests: Dr. Bea would like to disclose board membership for the Global Health and Body Composition Institute and a contract with Disarm Therapeutics, Inc. for an unrelated research project. Dr. Bea also serves as a consultant for the WHI Western Region and as a reviewer for the WHI Papers and Proposals Committee. Dr. Thomson would like to disclose serving as Chair of the WHI Steering Committee. All other authors report no conflicts of interest.
Databáze:	MEDLINE
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