Tear meniscus particle analysis with anterior segment optical coherence tomography in keratoconus.

Autor:	Seyyar SA; Ophthalmology Department, Gaziantep University Hospital, Gaziantep, Turkey., Büyükbayram Ş; Ophthalmology Department, Gaziantep University Hospital, Gaziantep, Turkey., Soysal GG; Ophthalmology Clinic, Ersin Arslan Education and Research Hospital, Gaziantep, Turkey., Ayla S; Ophthalmology Department, Gaziantep University Hospital, Gaziantep, Turkey., Doğan L; Ophthalmology Clinic, Kilis State Hospital, Kilis, Turkey., Tokuç EÖ; Ophthalmology Department, Kocaeli University Hospital, Kocaeli, Turkey., Mercanlı M; Ophthalmology Clinic, Dünyagöz Hospital, Adana, Turkey., Mete A; Ophthalmology Department, Gaziantep University Hospital, Gaziantep, Turkey.
Jazyk:	angličtina
Zdroj:	Indian journal of ophthalmology [Indian J Ophthalmol] 2024 Aug 01; Vol. 72 (8), pp. 1136-1141. Date of Electronic Publication: 2024 Jul 29.
DOI:	10.4103/IJO.IJO_3298_23
Abstrakt:	Purpose: To perform tear meniscus particle analysis using anterior segment spectral domain-optical coherence tomography (SD-OCT) and ImageJ software in keratoconus patients. Methods: A total of 76 participants (76 eyes) were included in the study. A comprehensive analysis of tear meniscus parameters, including tear meniscus height (TMH), tear meniscus depth (TMD), tear meniscus turbidity (TMT), and percentage of area occupied by particles (PAOP) within the meniscus, was performed in kerataconus patients and healthy controls. Results: TMT was significantly higher in the keratoconus group, while PAOP was significantly lower (P < 0.05). However, TMH and TMD did not show significant differences between the two groups (P > 0.05). There was a negative correlation observed between TMT and PAOP. In binary logistic regression analysis, TMT and Schirmer score were found to be the most influential factors in predicting keratoconus (odds ratio [OR] = 0.995, P = 0.039 and OR = 1.143, P = 0.021, respectively). Conclusion: This study revealed novel findings on analysis of the tear film in keratoconus patients, with higher TMT and lower POAP levels in the keratoconus group compared to the healthy control group. (Copyright © 2024 Copyright: © 2024 Indian Journal of Ophthalmology.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu