Burden and factors associated with occupational tuberculosis infection among high-risk workers in Lahore District, Pakistan.

Autor:	Jabeen C; Department of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, Pakistan., Mushtaq MH; Department of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, Pakistan., Ali Khan J; Department of Veterinary Medicine, University of Veterinary and Animal Sciences, Lahore, Pakistan., Umbreen G; Department of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, Pakistan., Saeed MS; Institute of TB and Chest Medicine, King Edward Medical University, Lahore, Pakistan., Sadiq S; Department of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, Pakistan., Maqsood R; Department of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, Pakistan., Rashid HB; Department of Veterinary Surgery, University of Veterinary and Animal Sciences, Lahore, Pakistan., Asif M; Provincial TB Control Program, Punjab, Pakistan., Iqbal K; Infectious Disease Hospital, Bilal Ganj, Lahore, Pakistan., Ahmad S; Infectious Disease Hospital, Bilal Ganj, Lahore, Pakistan., Chaudhry M; Department of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, Pakistan.
Jazyk:	angličtina
Zdroj:	Journal of infection in developing countries [J Infect Dev Ctries] 2024 Jul 29; Vol. 18 (7), pp. 1041-1049. Date of Electronic Publication: 2024 Jul 29.
DOI:	10.3855/jidc.17965
Abstrakt:	Introduction: The main objective of the study was to estimate the burden of occupational tuberculosis infection in high-risk occupational workers and to identify risk factors associated with the prevalence of Mycobacterium tuberculosis complex (MTBC). Methodology: An analytical cross-sectional study was conducted among high-risk occupational workers including veterinarians, abattoir workers, animal handlers, livestock farmers, and microbiology laboratory workers. Sputum samples were collected from 100 participants and polymerase chain reaction (PCR) tests were done to diagnose tuberculosis (TB) infection. Data on potential risk factors was collected in a pre-designed questionnaire. The MTBC prevalence ratio was estimated. Logistic regression analysis was conducted to identify risk factors and the crude odds ratio (OR) was calculated. Results: Among the 100 enrolled high risk occupational workers, the prevalence of MTBC was 46% (95% CI: 35.98-56.25). Living in a joint family (OR 3.85, 95% CI: 1.58-9.37), and use of unpasteurized milk (OR 3.42, 95% CI: 1.4-8.39), were significantly associated with MTBC infection. Conclusions: Tuberculosis is a significant health burden in high-risk occupational groups, especially animal handlers and laboratory workers, in Lahore, Pakistan. The study also emphasized the need for formal work-related training, and enhanced zoonotic TB awareness among occupational workers. Competing Interests: No Conflict of Interest is declared (Copyright (c) 2024 Chanda Jabeen, Muhammad Hassan Mushtaq, Jawaria Ali Khan, Gulshan Umbreen, Muhammad Saqib Saeed, Shakera Sadiq, Rubab Maqsood, Hamad Bin Rashid, Muhammad Asif, Khalid Iqbal, Sohail Ahmad, Mamoona Chaudhry.)
Databáze:	MEDLINE
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