COVID-19 vaccine hesitancy worldwide and its associated factors: a systematic review and meta-analysis.

Autor:	Baghani M; Functional Neurosurgery Research Center, Shohada Tajrish Comprehensive Neurosurgical Center of Excellence, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Cognitive and Neuroscience Research Center (CNRC), Tehran Medical Sciences, Islamic Azad University, Tehran, Iran., Fathalizade F; Functional Neurosurgery Research Center, Shohada Tajrish Comprehensive Neurosurgical Center of Excellence, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Cognitive and Neuroscience Research Center (CNRC), Tehran Medical Sciences, Islamic Azad University, Tehran, Iran., Loghman AH; USERN Office, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Network of Interdisciplinarity in Neonates and Infants (NINI), Universal Scientific Education and Research Network (USERN), Tehran, Iran., Samieefar N; USERN Office, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Network of Interdisciplinarity in Neonates and Infants (NINI), Universal Scientific Education and Research Network (USERN), Tehran, Iran., Ghobadinezhad F; Student Research Committee, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.; USERN Office, Kermanshah University of Medical Sciences, Kermanshah, Iran.; Network of Interdisciplinarity in Neonates and Infants (NINI), Universal Scientific Education and Research Network (USERN), Tehran, Iran., Rashedi R; USERN Office, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Network of Interdisciplinarity in Neonates and Infants (NINI), Universal Scientific Education and Research Network (USERN), Tehran, Iran., Baghsheikhi H; USERN Office, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Network of Interdisciplinarity in Neonates and Infants (NINI), Universal Scientific Education and Research Network (USERN), Tehran, Iran., Sodeifian F; USERN Office, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; USERN Office, Kermanshah University of Medical Sciences, Kermanshah, Iran., Rahimzadegan M; Functional Neurosurgery Research Center, Shohada Tajrish Comprehensive Neurosurgical Center of Excellence, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; USERN Office, Functional Neurosurgery Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Akhlaghdoust M; Functional Neurosurgery Research Center, Shohada Tajrish Comprehensive Neurosurgical Center of Excellence, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; USERN Office, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; USERN Office, Functional Neurosurgery Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Network of Interdisciplinarity in Neonates and Infants (NINI), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
Jazyk:	angličtina
Zdroj:	Science in One Health [Sci One Health] 2023 Nov 14; Vol. 2, pp. 100048. Date of Electronic Publication: 2023 Nov 14 (Print Publication: 2023).
DOI:	10.1016/j.soh.2023.100048
Abstrakt:	Introduction: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has taken a toll on humans, and the development of effective vaccines has been a promising tool to end the pandemic. However, for a vaccination program to be successful, a considerable proportion of the community must be vaccinated. Hence, public acceptance of coronavirus disease 2019 (COVID-19) vaccines has become the key to controlling the pandemic. Recent studies have shown vaccine hesitancy increasing over time. This systematic review aims to evaluate the COVID-19 vaccine hesitancy rate and related factors in different communities. Method: A comprehensive search was performed in MEDLINE (via PubMed), Scopus, and Web of Science from January 1, 2019 to January 31, 2022. All relevant descriptive and observational studies (cross-sectional and longitudinal) on vaccine hesitancy and acceptance were included in this systematic review. In the meta-analysis, odds ratio (OR) was used to assess the effects of population characteristics on vaccine hesitancy, and event rate (acceptance rate) was the effect measure for overall acceptance. Publication bias was assessed using the funnel plot, Egger's test, and trim-and-fill methods. Result: A total of 135 out of 6,417 studies were included after screening. A meta-analysis of 114 studies, including 849,911 participants, showed an overall acceptance rate of 63.1%. In addition, men, married individuals, educated people, those with a history of flu vaccination, those with higher income levels, those with comorbidities, and people living in urban areas were less hesitant. Conclusion: Increasing public awareness of the importance of COVID-19 vaccines in overcoming the pandemic is crucial. Being men, living in an urban region, being married or educated, having a history of influenza vaccination, having a higher level of income status, and having a history of comorbidities are associated with higher COVID-19 vaccine acceptance. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (© 2023 The Author(s).)
Databáze:	MEDLINE
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