Expanding the Donor Pool to the Ultimate Level: Introducing the Revolutionary Hybrid Dual Graft Liver Transplant Using Domino and Living Donors.

Autor:	Zidan A; Organ Transplant Center of Excellence, King Fahad Specialist Hospital, Dammam, Saudi Arabia., Momani H; Organ Transplant Center of Excellence, King Fahad Specialist Hospital, Dammam, Saudi Arabia., Sengupta B; Organ Transplant Center of Excellence, King Fahad Specialist Hospital, Dammam, Saudi Arabia., Abdullah R; Organ Transplant Center of Excellence, King Fahad Specialist Hospital, Dammam, Saudi Arabia., Bader R; Organ Transplant Center of Excellence, King Fahad Specialist Hospital, Dammam, Saudi Arabia., Khan I; Organ Transplant Center of Excellence, King Fahad Specialist Hospital, Dammam, Saudi Arabia., Tawfeeq M; Organ Transplant Center of Excellence, King Fahad Specialist Hospital, Dammam, Saudi Arabia., Al Qahtani M; Organ Transplant Center of Excellence, King Fahad Specialist Hospital, Dammam, Saudi Arabia.
Jazyk:	angličtina
Zdroj:	Transplantation direct [Transplant Direct] 2024 Jul 26; Vol. 10 (8), pp. e1681. Date of Electronic Publication: 2024 Jul 26 (Print Publication: 2024).
DOI:	10.1097/TXD.0000000000001681
Abstrakt:	Background: Innovative solutions are crucial as the demand for liver transplants continues to outpace available grafts. Dual graft liver transplantation offers a promising avenue to address graft volume challenges while minimizing donor risks. This report introduces a groundbreaking approach, combining a full organ domino donor graft with a living donor graft for a hybrid dual graft liver transplant. Brief Report: A 2-y-old child with Maple syrup urine disease and a 40-y-old adult with end-stage liver disease became the focus of this unique case. A hybrid dual graft liver transplant was executed, uniting the domino donor's full organ graft with a living donor's left lateral segment. Precise vascular and biliary reconstructions facilitated a successful transplant. Conclusions: The hybrid dual graft liver transplant, merging domino donor and living donor grafts, presents a viable strategy to combat graft shortages, particularly in regions predominantly reliant on living donor transplants. Despite challenges, this pioneering approach should be embraced by established liver transplant centers because it enables concurrent living donor liver transplantation while prioritizing donor safety and recipient outcomes. (Copyright © 2024 The Author(s). Transplantation Direct. Published by Wolters Kluwer Health, Inc.)
Databáze:	MEDLINE
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