Ameloblastoma of the Maxilla With Distant Metastases to the Lungs: A Case Report and Literature Review.

Autor: Al-Hakami HA; Otolaryngology: Head and Neck Surgical Oncology and Reconstructive Surgery, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Ministry of the National Guard - Health Affairs, Jeddah, SAU., I Awad B; College of Medicine, Otolaryngology-Head & Neck Surgery, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Ministry of the National Guard - Health Affairs, Jeddah, SAU., Alsolamy RM; College of Medicine, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Jeddah, SAU., Al-Garni M; College of Medicine, Otolaryngology - Head & Neck Surgery, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Ministry of the National Guard - Health Affairs, Jeddah, SAU., Alshareef MA; Otolaryngology - Head and Neck Surgery, King Abdulaziz Medical City, Jeddah, SAU., Essatari M; Pathology and Laboratory Medicine, King Abdul-Aziz Medical City, Western Region (WR) National Guard Health Affairs, King Abdullah International Medical Research Center, Ministry of the National Guard - Health Affairs, Jeddah, SAU.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Jun 26; Vol. 16 (6), pp. e63233. Date of Electronic Publication: 2024 Jun 26 (Print Publication: 2024).
DOI: 10.7759/cureus.63233
Abstrakt: Maxillary ameloblastoma is one of the rarest odontogenic epithelial tumors encountered, as 80% of ameloblastomas are seen within the mandible. Ameloblastoma is usually incidentally detected in the third to fourth decades of life, as most patients remain asymptomatic; yet some patients may complain of a slowly growing, painless swelling. We present a case of maxillary ameloblastoma with pulmonary metastasis along with a brief literature review. A 17-year-old male initially presented with painless right facial swelling, which, on examination, was non-tender, immobile, irregular, pink in color, with a high tendency to bleed, and located in the mucogingival sulcus with a size of around 3x2.5 cm. Following comprehensive radiological and histopathological evaluation, the diagnosis of ameloblastoma characterized by the coexistence of plexiform and follicular patterns was confirmed. The patient underwent a partial right maxillectomy with an obturator sealing the hard palate. Unfortunately, multiple local recurrences were identified afterward, and eventually, pulmonary metastasis was detected. Early and adequate surgical resection of the primary tumor is crucial to prevent further recurrences in patients with ameloblastoma. This could be achieved by providing a tight postoperative follow-up schedule while paying special attention to the lungs, neck, and other suspicious areas to detect metastasis as early as possible.
Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.
(Copyright © 2024, Al-Hakami et al.)
Databáze: MEDLINE