Right ventricular dysfunction: pathophysiology, experimental models, evaluation, and treatment.

Autor: Real C; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain; Servicio de Cardiología, Hospital Universitario Clínico San Carlos, Madrid, Spain., Pérez-García CN; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain., Galán-Arriola C; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain., García-Lunar I; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain; Servicio de Cardiología, Hospital Universitario La Moraleja, Madrid, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Spain., García-Álvarez A; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Spain; Servicio de Cardiología, Instituto Clínic Cardiovascular (ICCV), Hospital Clínic, Barcelona, Spain; Universitat de Barcelona, Barcelona, Spain. Electronic address: anagarci@clinic.cat.
Jazyk: English; Spanish; Castilian
Zdroj: Revista espanola de cardiologia (English ed.) [Rev Esp Cardiol (Engl Ed)] 2024 Nov; Vol. 77 (11), pp. 957-970. Date of Electronic Publication: 2024 Jul 26.
DOI: 10.1016/j.rec.2024.05.018
Abstrakt: Interest in the right ventricle has substantially increased due to advances in knowledge of its pathophysiology and prognostic implications across a wide spectrum of diseases. However, we are still far from understanding the multiple mechanisms that influence right ventricular dysfunction, its evaluation continues to be challenging, and there is a shortage of specific treatments in most scenarios. This review article aims to update knowledge about the physiology of the right ventricle, its transition to dysfunction, diagnostic tools, and available treatments from a translational perspective.
(Copyright © 2024 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.)
Databáze: MEDLINE
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