Leptospirosis in central India: A retrospective study to explore burden of tropical illness.

Autor: Manjunathachar HV; Division of Virology & Zoonoses, ICMR- National Institute of Research in Tribal Health (NIRTH), Jabalpur, 482003, Madhya Pradesh, India. Electronic address: manjunathachar632@gmail.com., Barde PV; Division of Virology & Zoonoses, ICMR- National Institute of Research in Tribal Health (NIRTH), Jabalpur, 482003, Madhya Pradesh, India; ICMR-National Institute of Virology, Pune, Maharastra, 411001, India. Electronic address: pradip_barde@hotmail.com., Chouksey V; Division of Virology & Zoonoses, ICMR- National Institute of Research in Tribal Health (NIRTH), Jabalpur, 482003, Madhya Pradesh, India. Electronic address: vivekchouksey06@gmail.com., Tiwari P; Division of Virology & Zoonoses, ICMR- National Institute of Research in Tribal Health (NIRTH), Jabalpur, 482003, Madhya Pradesh, India. Electronic address: prakashtiwari90@gmail.com., Mathapati B; ICMR-National Institute of Virology, Pune, Maharastra, 411001, India. Electronic address: basavaraj.mathapati@gmail.com., Shrivastava S; Division of Non-Communicable Diseases, ICMR- National Institute of Research in Tribal Health (NIRTH), Jabalpur, 482003, Madhya Pradesh, India. Electronic address: dr.ssuyesh@gmail.com., Chakma T; Division of Non-Communicable Diseases, ICMR- National Institute of Research in Tribal Health (NIRTH), Jabalpur, 482003, Madhya Pradesh, India. Electronic address: tapas_chakma@rediffmail.com.
Jazyk: angličtina
Zdroj: Indian journal of medical microbiology [Indian J Med Microbiol] 2024 Sep-Oct; Vol. 51, pp. 100689. Date of Electronic Publication: 2024 Aug 01.
DOI: 10.1016/j.ijmmb.2024.100689
Abstrakt: Leptospirosis, an underdiagnosed zoonotic disease in India, was studied retrospectively in Madhya Pradesh, Central India. Between 2018 and 2019, 2617 samples from patients with hepatitis-related symptoms were collected. Of these, 518 tested negative for hepatitis and other tropical viral diseases under the VRDL project were analyzed for leptospira IgM using ELISA. 68 (13.12%) were positive for leptospirosis. Common symptoms included fever (97.45%) and jaundice (42.27%), with renal involvement in 30.88% of cases. Higher incidence was observed in the 31-60 age group, especially during monsoon and post-monsoon seasons. The study highlights the need for increased clinician awareness and inclusion of leptospirosis in screening panels to differentiate tropical illnesses in India.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the research work reported here.
(Copyright © 2024 Indian Association of Medical Microbiologists. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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