An Overview of Methotrexate Indications in Skin Diseases.

Autor: Mocanu M; Department of Dermatology, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.; Dermatology Clinic, 'St. Spiridon' County Emergency Clinical Hospital, 700115 Iasi, Romania., Procopciuc D; Dermatology Clinic, 'St. Spiridon' County Emergency Clinical Hospital, 700115 Iasi, Romania., Gheucă-Solovăstru DF; Faculty of Medicine, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania., Popescu IA; Department of Dermatology, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.; Dermatology Clinic, 'St. Spiridon' County Emergency Clinical Hospital, 700115 Iasi, Romania., Olinici DT; Dermatology Clinic, 'St. Spiridon' County Emergency Clinical Hospital, 700115 Iasi, Romania.; Faculty of Medicine, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania., Pătrașcu AI; Dermatology Clinic, 'St. Spiridon' County Emergency Clinical Hospital, 700115 Iasi, Romania., Vâță D; Department of Dermatology, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.; Dermatology Clinic, 'St. Spiridon' County Emergency Clinical Hospital, 700115 Iasi, Romania., Gheucă-Solovăstru L; Department of Dermatology, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.; Dermatology Clinic, 'St. Spiridon' County Emergency Clinical Hospital, 700115 Iasi, Romania.
Jazyk: angličtina
Zdroj: Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2024 Jun 21; Vol. 60 (7). Date of Electronic Publication: 2024 Jun 21.
DOI: 10.3390/medicina60071024
Abstrakt: Methotrexate is an immunosuppressive drug with remarkable therapeutic results in the treatment of autoimmune and proliferative skin diseases. Although it has been more than half a century since it was first introduced into the therapeutic arsenal of dermatologists, there are currently no standardized therapeutic protocols regarding the prescription of methotrexate in dermatology, with the exception of psoriasis treatment. This review aims to highlight the indications and benefits of methotrexate beyond psoriasis, with a focus on a wide range of inflammatory, vesiculobullous, and proliferative dermatological pathologies.
Databáze: MEDLINE