| Autor: |
Lee CY; Institute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan.; Nobel Eye Institute, Taipei 115, Taiwan.; Department of Ophthalmology, Jen-Ai Hospital Dali Branch, Taichung 402, Taiwan., Lian IB; Institute of Statistical and Information Science, National Changhua University of Education, Changhua 500, Taiwan., Chen HC; Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou 333, Taiwan.; Center for Tissue Engineering, Chang Gung Memorial Hospital, Linkou 333, Taiwan.; Department of Medicine, Chang Gung University College of Medicine, Taoyuan 333, Taiwan., Huang CT; Department of Ophthalmology, Chung Shan Medical University Hospital, Taichung 402, Taiwan.; Department of Ophthalmology, School of Medicine, Chung Shan Medical University, Taichung 402, Taiwan., Huang JY; Department of Medical Research, Chung Shan Medical University Hospital, Taichung 402, Taiwan., Yang SF; Institute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan.; Department of Medical Research, Chung Shan Medical University Hospital, Taichung 402, Taiwan., Chang CK; Nobel Eye Institute, Taipei 115, Taiwan.; Department of Optometry, Da-Yeh University, Chunghua 515, Taiwan. |
| Abstrakt: |
We aimed to evaluate the postoperative visual and refractive outcomes between the first- and second-generation keratorefractive lenticule extraction (KLEx) surgeries. A retrospective cohort study was conducted and patients who had received first- and second-generation KLEx surgeries were enrolled. A total of 80 and 80 eyes were categorized into the first and second KLEx groups after exclusion, respectively. The primary outcomes were the postoperative uncorrected distance visual acuity (UDVA), spherical equivalent (SE), and safety indexes. An independent t -test and generalized estimate equation were implemented to compare the primary outcomes between the two groups. After the KLEx surgery, the UDVA showed no significant difference between the two groups throughout the study period (all p > 0.05), and the postoperative SE and safety index were also statistically identical between the two groups during the follow-up interval (all p > 0.05). There was a similar trend of visual recovery between the two groups (aOR: 0.967; 95% CI: 0.892-1.143; p = 0.844), while the amplitude of the SE change was significantly lower in the second KLEx group (aOR: 0.760; 95% CI: 0.615-0.837; p = 0.005). Nine and two unintended initial dissection of the posterior plane (UIDPP) occurred intraoperatively in the first and second KLEx groups, respectively, and the second group showed a lower risk of UIDPP ( p = 0.032). In conclusion, the efficiency, predictability, and safety are similar between first- and second-generation KLEx surgeries. |
