A Comparative Analysis of MRSA: Epidemiology and Antibiotic Resistance in Greece and Romania.

Autor: Vittorakis E; Department of Microbiology, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.; Department of Cell and Molecular Biology, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.; Agios Georgios General Hospital of Chania, 73100 Crete, Greece., Vica ML; Department of Cell and Molecular Biology, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania., Zervaki CO; Agios Georgios General Hospital of Chania, 73100 Crete, Greece., Vittorakis E; Agios Georgios General Hospital of Chania, 73100 Crete, Greece., Maraki S; Department of Clinical Microbiology and Microbial Pathogenesis, University Hospital of Heraklion, 70013 Crete, Greece., Mavromanolaki VE; Department of Clinical Microbiology and Microbial Pathogenesis, University Hospital of Heraklion, 70013 Crete, Greece., Schürger ME; Department of Cell and Molecular Biology, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania., Neculicioiu VS; Department of Microbiology, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania., Papadomanolaki E; Agios Georgios General Hospital of Chania, 73100 Crete, Greece., Junie LM; Department of Microbiology, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Jazyk: angličtina
Zdroj: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 09; Vol. 25 (14). Date of Electronic Publication: 2024 Jul 09.
DOI: 10.3390/ijms25147535
Abstrakt: This study provides a comparative analysis of 243 Methicillin-resistant Staphylococcus aureus (MRSA) isolated strains from Greece and Romania, focusing on their epidemiology and antibiotic resistance patterns. Laboratory procedures included phenotypic and automated identification methods, susceptibility testing, DNA isolation, and PCR for detecting antibiotic resistance genes ( MecA , SCCmec ). Our study results show significant regional differences. In both regions, males have higher MRSA infection rates than females, but the percentages vary. Greece has a higher incidence of MRSA in younger age groups compared to Romania. The majority of MRSA infections occur in inpatient settings in both countries, highlighting the necessity for enhanced infection control measures. Antibiotic resistance profiles reveal higher resistance to several antibiotics in Greece compared to Romania. A molecular analysis shows a widespread distribution of antibiotic resistance genes among MRSA isolates in Greece. These results highlight the necessity for accomplished preventive strategies and optimized treatment protocols.
Databáze: MEDLINE
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