High-Resolution Peripheral Quantitative Computed Tomography in Rheumatic Diseases: A New Option for Knee Osteoarthritis.

Autor: Boyd SK; Department of Radiology, McCaig Institute for Bone and Joint Health, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Department of Biomedical Engineering, Schulich School of Engineering, University of Calgary, Calgary, Alberta, Canada. Electronic address: skboyd@ucalgary.ca.
Jazyk: angličtina
Zdroj: Radiologic clinics of North America [Radiol Clin North Am] 2024 Sep; Vol. 62 (5), pp. 903-912. Date of Electronic Publication: 2024 Mar 19.
DOI: 10.1016/j.rcl.2024.02.010
Abstrakt: High-resolution peripheral quantitative computed tomography (HR-pQCT) provides a new opportunity for the noninvasive measurement of bone microarchitecture in patient research of rheumatic disease in joints of the extremities. Rheumatoid arthritis of the hand and osteoarthritis of the knee are highly prevalent and there are no cures, so an improved understanding of the etiology of these diseases, particularly when combining HR-pQCT with other imaging modalities, is important to develop new disease management strategies. Analysis of HR-pQCT data is challenging due to the large size of the datasets, but the field continues to rapidly develop, and there is excellent opportunity to integrate sophisticated analyses for this novel research tool.
Competing Interests: Disclosure The author has nothing to disclose.
(Copyright © 2024 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE