Emergence and properties of adult mammalian epidermal stem cells.

Autor: Gadre P; Directors' Unit, EMBL-Heidelberg, Meyerhofstr. 1, 69117, Heidelberg, Germany., Markova P; Directors' Unit, EMBL-Heidelberg, Meyerhofstr. 1, 69117, Heidelberg, Germany., Ebrahimkutty M; Directors' Unit, EMBL-Heidelberg, Meyerhofstr. 1, 69117, Heidelberg, Germany., Jiang Y; Directors' Unit, EMBL-Heidelberg, Meyerhofstr. 1, 69117, Heidelberg, Germany., Bouzada FM; Directors' Unit, EMBL-Heidelberg, Meyerhofstr. 1, 69117, Heidelberg, Germany., Watt FM; Directors' Unit, EMBL-Heidelberg, Meyerhofstr. 1, 69117, Heidelberg, Germany. Electronic address: Fiona.watt@embo.org.
Jazyk: angličtina
Zdroj: Developmental biology [Dev Biol] 2024 Nov; Vol. 515, pp. 129-138. Date of Electronic Publication: 2024 Jul 24.
DOI: 10.1016/j.ydbio.2024.07.014
Abstrakt: In this review we discuss how the mammalian interfollicular epidermis forms during development, maintains homeostasis, and is repaired following wounding. Recent studies have provided new insights into the relationship between the stem cell compartment and the differentiating cell layers; the ability of differentiated cells to dedifferentiate into stem cells; and the epigenetic memory of epidermal cells following wounding.
(Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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