Resilience of the replacing dentition in adult reptiles.

Autor: Henriquez JI; Life Sciences Institute and Faculty of Dentistry, University of British Columbia, Canada., Richman JM; Life Sciences Institute and Faculty of Dentistry, University of British Columbia, Canada. Electronic address: richman@dentistry.ubc.ca.
Jazyk: angličtina
Zdroj: Developmental biology [Dev Biol] 2024 Dec; Vol. 516, pp. 71-81. Date of Electronic Publication: 2024 Jul 24.
DOI: 10.1016/j.ydbio.2024.07.013
Abstrakt: The dentition is critical to animal survival and teeth are present in modern vertebrates including teleost fish, sharks, amphibians, mammals and reptiles. The developmental processes that give rise to teeth are not just preserved through evolution but also share high level of similarity with the embryogenesis of other ectodermal organs. In this review we go beyond the embryonic phase of tooth development to life-long tooth replacement. We will address the origins of successional teeth, the location of putative tissue-resident stem cells, how de novo tooth formation continues throughout life and how teeth are shed in a spatially and temporally controlled manner. We review the evidence that the dental epithelium, which is the earliest recognizable dental structure in the reptilian dentition, serves as a putative niche for tissue-resident epithelial stem cells and recent molecular findings from transcriptomics carried out in reptilian dentitions. We discuss how odontoclasts resorb the primary tooth allowing eruption of the successional tooth. The reptiles, particularly lizards, are emerging as some of the most accessible animals to study tooth replacement which has relevance to evolution of the dentition and human dental disorders.
(Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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