Lignanamides: A comprehensive review of chemical constituents, biological activities, extraction methods and synthetic pathway.

Autor: Sun J; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Laboratory of Quality and Safety Risk Assessment on Agro-products Processing, Ministry of Agriculture and Rural Affairs, Key Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Beijing, China., Tong LT; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Laboratory of Quality and Safety Risk Assessment on Agro-products Processing, Ministry of Agriculture and Rural Affairs, Key Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Beijing, China., Tu PF; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, People's Republic of China., Chen LL; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Laboratory of Quality and Safety Risk Assessment on Agro-products Processing, Ministry of Agriculture and Rural Affairs, Key Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Beijing, China; Pharmaceutical Engineering Technology Research Center, Harbin University of Commerce, Harbin, China., Xu X; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Laboratory of Quality and Safety Risk Assessment on Agro-products Processing, Ministry of Agriculture and Rural Affairs, Key Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Beijing, China., Song Y; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Laboratory of Quality and Safety Risk Assessment on Agro-products Processing, Ministry of Agriculture and Rural Affairs, Key Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Beijing, China; Pharmaceutical Engineering Technology Research Center, Harbin University of Commerce, Harbin, China., Yang XX; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Laboratory of Quality and Safety Risk Assessment on Agro-products Processing, Ministry of Agriculture and Rural Affairs, Key Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Beijing, China., Guo ZB; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Laboratory of Quality and Safety Risk Assessment on Agro-products Processing, Ministry of Agriculture and Rural Affairs, Key Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Beijing, China., Zou X; Pharmaceutical Engineering Technology Research Center, Harbin University of Commerce, Harbin, China., Sun CX; Pharmaceutical Engineering Technology Research Center, Harbin University of Commerce, Harbin, China., Mi Y; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Laboratory of Quality and Safety Risk Assessment on Agro-products Processing, Ministry of Agriculture and Rural Affairs, Key Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Beijing, China., Fan B; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Laboratory of Quality and Safety Risk Assessment on Agro-products Processing, Ministry of Agriculture and Rural Affairs, Key Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Beijing, China; Western Agricultural Research Center, Chinese Academy of Agricultural Sciences, Changji 831100, China. Electronic address: fanbei517@163.com., Wang FZ; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Laboratory of Quality and Safety Risk Assessment on Agro-products Processing, Ministry of Agriculture and Rural Affairs, Key Laboratory of Agro-products Quality and Safety Control in Storage and Transport Process, Beijing, China; Western Agricultural Research Center, Chinese Academy of Agricultural Sciences, Changji 831100, China. Electronic address: wangfengzhong@sina.com.
Jazyk: angličtina
Zdroj: Food chemistry [Food Chem] 2024 Dec 01; Vol. 460 (Pt 1), pp. 140459. Date of Electronic Publication: 2024 Jul 15.
DOI: 10.1016/j.foodchem.2024.140459
Abstrakt: Lignanamides are a class of compounds containing amide functional groups in lignans. These compounds have excellent anti-inflammatory and neuroprotective, which have shown great potential in terms of food additives, medicine and health supplement. We summarized the recent progress of lignanamides, including chemical constituents, extraction methods, biological activities, and synthetic pathways. The structures were classified according to an updated nomenclature system, can be classified into sixteen types and have certain roles in many respects such as anti-inflammatory, anti-cancer, and antioxidative, which may be important source of materials for functional food. The potential and limitations of different extraction method, chromatographic packing, and synthetic pathway are analyzed. Notably, this review provides an overview of synthesis pathways and applications of lignanamides, further research is needed to improve extraction efficiency and synthesis method, especially in a greener way for better application.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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