Influence of a Solid Surface on PNIPAM Microgel Films.

Autor:	Nigro V; ENEA C.R. Frascati, Nuclear Department, Via Enrico Fermi 45, 00044 Frascati, Italy.; Institute for Complex Systems, National Research Council (ISC-CNR), Sapienza University of Rome, P.le A. Moro 2, 00185 Rome, Italy., Angelini R; Institute for Complex Systems, National Research Council (ISC-CNR), Sapienza University of Rome, P.le A. Moro 2, 00185 Rome, Italy.; Physics Department, Sapienza University, P.le Aldo Moro 2, 00185 Rome, Italy., Buratti E; Institute for Complex Systems, National Research Council (ISC-CNR), Sapienza University of Rome, P.le A. Moro 2, 00185 Rome, Italy.; Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, Via Luigi Borsari 46, 14412 Ferrara, Italy., Colantonio C; Institute for Complex Systems, National Research Council (ISC-CNR), Sapienza University of Rome, P.le A. Moro 2, 00185 Rome, Italy., D'Amato R; ENEA C.R. Frascati, Nuclear Department, Via Enrico Fermi 45, 00044 Frascati, Italy., Dinelli F; National Institute of Optics (INO-CNR), Via Moruzzi 1, 56124 Pisa, Italy., Franco S; Institute for Complex Systems, National Research Council (ISC-CNR), Sapienza University of Rome, P.le A. Moro 2, 00185 Rome, Italy.; Physics Department, Sapienza University, P.le Aldo Moro 2, 00185 Rome, Italy., Limosani F; ENEA C.R. Casaccia, Nuclear Department, Via Anguillarese, 301, 00123 Rome, Italy., Montereali RM; ENEA C.R. Frascati, Nuclear Department, Via Enrico Fermi 45, 00044 Frascati, Italy., Nichelatti E; ENEA C.R. Casaccia, Nuclear Department, Via Anguillarese, 301, 00123 Rome, Italy., Piccinini M; ENEA C.R. Frascati, Nuclear Department, Via Enrico Fermi 45, 00044 Frascati, Italy., Vincenti MA; ENEA C.R. Frascati, Nuclear Department, Via Enrico Fermi 45, 00044 Frascati, Italy., Ruzicka B; Institute for Complex Systems, National Research Council (ISC-CNR), Sapienza University of Rome, P.le A. Moro 2, 00185 Rome, Italy.; Physics Department, Sapienza University, P.le Aldo Moro 2, 00185 Rome, Italy.
Jazyk:	angličtina
Zdroj:	Gels (Basel, Switzerland) [Gels] 2024 Jul 18; Vol. 10 (7). Date of Electronic Publication: 2024 Jul 18.
DOI:	10.3390/gels10070473
Abstrakt:	Stimuli-responsive microgels have attracted great interest in recent years as building blocks for fabricating smart surfaces with many technological applications. In particular, PNIPAM microgels are promising candidates for creating thermo-responsive scaffolds to control cell growth and detachment via temperature stimuli. In this framework, understanding the influence of the solid substrate is critical for tailoring microgel coatings to specific applications. The surface modification of the substrate is a winning strategy used to manage microgel-substrate interactions. To control the spreading of microgel particles on a solid surface, glass substrates are coated with a PEI or an APTES layer to improve surface hydrophobicity and add positive charges on the interface. A systematic investigation of PNIPAM microgels spin-coated through a double-step deposition protocol on pristine glass and on functionalised glasses was performed by combining wettability measurements and Atomic Force Microscopy. The greater flattening of microgel particles on less hydrophilic substrates can be explained as a consequence of the reduced shielding of the water-substrate interactions that favors electrostatic interactions between microgels and the substrate. This approach allows the yielding of effective control on microgel coatings that will help to unlock new possibilities for their application in biomedical devices, sensors, or responsive surfaces.
Databáze:	MEDLINE
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