Ethnomedicinal Uses, Phytochemistry, Pharmacology, and Toxicology of Ruellia tuberosa L.: A Review.

Autor: Sharma A; Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Ghudda, Bathinda, India-, 151401.; Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi, Jharkhand, India-, 835215., Kumar A; Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Ghudda, Bathinda, India-, 151401., Singh AK; Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Ghudda, Bathinda, India-, 151401., Kumar KJ; Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi, Jharkhand, India-, 835215., Narasimhan B; Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, Haryana, India-, 124001., Kumar P; Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Ghudda, Bathinda, India-, 151401.
Jazyk: angličtina
Zdroj: Chemistry & biodiversity [Chem Biodivers] 2024 Aug; Vol. 21 (8), pp. e202400292. Date of Electronic Publication: 2024 Jul 26.
DOI: 10.1002/cbdv.202400292
Abstrakt: Natural Products continue to be the purest source of physiologically active molecules employed in the identification of possible lead compounds in the drug discovery process. Acanthaceae is a big plant family with around 2500 species, found primarily in subtropical and tropical regions, as well as the Mediterranean, Australia, and the United States. Several species of the Acanthaceae family have been used traditionally to treat a variety of diseases, including gastrointestinal and cardiovascular ailments, etc. Ruellia tuberosa commonly known as "Mexican Bluebell" is a perennial herb that originated in Central America and has spread to some countries in the Southern tropics and Southeast Asia. It has been utilized as a traditional Rasayana plant from ancient times. R. tuberosa extracts and phytochemicals showed potent bioactivities, such as anticancer, anti-inflammatory, wound healing, antifungal, antimicrobial, anti-diabetic, hypoglycemic, hypolipidemic, gastro-protective, and anthelminthic activities. Chemical analyses have unveiled a range of bioactive constituents within the plant, including alkaloids, flavonoids, saponins, and phenolic compounds, suggestive of its therapeutic potential. Collectively, this review provides an overview of R. tuberosa, encompassing its traditional uses, ethnomedicinal importance, phytochemistry, pharmacological properties, and toxicity.
(© 2024 Wiley-VHCA AG, Zurich, Switzerland.)
Databáze: MEDLINE
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