A Man with Primary Hyperchylomicronemia with Triglyceride Levels Exceeding 11,000 mg/dL was Well Controlled by Pemafibrate Combined with Dietary Therapy: A Case Report.

Autor:	Ueda H; Department of Endocrinology and Metabolism, Sumitomo Hospital, Japan., Mineo R; Department of Endocrinology and Metabolism, Sumitomo Hospital, Japan., Sugiyama T; Department of Endocrinology and Metabolism, Sumitomo Hospital, Japan., Koseki M; Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Japan., Itoh Y; Department of Endocrinology and Metabolism, Sumitomo Hospital, Japan., Iwamoto R; Department of Endocrinology and Metabolism, Sumitomo Hospital, Japan., Tamba S; Department of Endocrinology and Metabolism, Sumitomo Hospital, Japan., Yamamoto K; Department of Endocrinology and Metabolism, Sumitomo Hospital, Japan., Yamada Y; Department of Endocrinology and Metabolism, Sumitomo Hospital, Japan., Hiraoka H; Department of Cardiology, Sumitomo Hospital, Japan., Matsuzawa Y; Department of Endocrinology and Metabolism, Sumitomo Hospital, Japan.
Jazyk:	angličtina
Zdroj:	Internal medicine (Tokyo, Japan) [Intern Med] 2024 Jul 25. Date of Electronic Publication: 2024 Jul 25.
DOI:	10.2169/internalmedicine.3946-24
Abstrakt:	A 50-year-old man with a triglyceride (TG) level of 11,397 mg/dL was admitted to our hospital. He consumed a high-fat and high-carbohydrate diet as well as more than 100 g of alcohol per day. He had type 2 diabetes and obesity and had previously suffered from severe acute pancreatitis twice. A genetic analysis revealed compound heterozygous mutations in APOA5 (c.56C>G and c.553G>T). In addition to low-fat meals and alcohol cessation, administration of pemafibrate lowered his triglyceride levels to <150 mg/dL.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu