Synthesis of green magnetic molecularly imprinted polymers for selective extraction of rifaximin in milk samples.

Autor: Farooq S; College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, 310058, China; Innovation Platform of Micro/Nano Technology for Biosensing, ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou, 311215, China., Xu L; College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, 310058, China; Innovation Platform of Micro/Nano Technology for Biosensing, ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou, 311215, China., Ullah S; School of Medicine, Keele University, Staffordshire, ST5 5BG, UK., Qin C; College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, 310058, China; Innovation Platform of Micro/Nano Technology for Biosensing, ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou, 311215, China., Ping J; College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, 310058, China; Innovation Platform of Micro/Nano Technology for Biosensing, ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou, 311215, China., Ying Y; College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, 310058, China; Innovation Platform of Micro/Nano Technology for Biosensing, ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou, 311215, China. Electronic address: ybying@zju.edu.cn.
Jazyk: angličtina
Zdroj: Food chemistry [Food Chem] 2024 Dec 01; Vol. 460 (Pt 1), pp. 140557. Date of Electronic Publication: 2024 Jul 19.
DOI: 10.1016/j.foodchem.2024.140557
Abstrakt: In this study, a new analytical method was developed using magnetic molecularly imprinted polymers (MMIPs) by employing eco-friendly supramolecular ternary deep eutectic solvents to synthesize these MMIPs for selective extraction of rifaximin. The characterization analysis and adsorption affinity investigation were conducted. The results showed fast adsorption (15 min) with high adsorption capacity (43.20 mg g -1 ) and selectivity for rifaximin. Various extraction parameters were optimized, achieving recoveries ranging from 86.67% to 99.47% in spiked milk samples using high-performance liquid chromatography (HPLC). The detection and quantification limits were 0.01 mg L -1 and 0.03 mg L -1 , respectively. The method exhibited low RSDs (<4.70%) and excellent selectivity, with MMIPs reusable up to seven times with only a 10% performance loss. This study proposes a convenient and reliable method for trace-level rifaximin extraction from milk using eco-friendly MMIPs.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024. Published by Elsevier Ltd.)
Databáze: MEDLINE
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