Portal thrombosis after surgical treatment of schistosomatic portal hypertension.

Autor:	Vasconcellos LS; Universidade Federal de Minas Gerais, School of Medicine - Belo Horizonte (MG), Brazil., Resende V; Universidade Federal de Minas Gerais, School of Medicine - Belo Horizonte (MG), Brazil., Rodrigues JBSR; Universidade Federal de Minas Gerais, School of Medicine - Belo Horizonte (MG), Brazil., Petroianu A; Universidade Federal de Minas Gerais, School of Medicine - Belo Horizonte (MG), Brazil.
Jazyk:	angličtina
Zdroj:	Revista da Associacao Medica Brasileira (1992) [Rev Assoc Med Bras (1992)] 2024 Jul 19; Vol. 70 (6), pp. e20231689. Date of Electronic Publication: 2024 Jul 19 (Print Publication: 2024).
DOI:	10.1590/1806-9282.20231689
Abstrakt:	Objective: Several studies have investigated the correlation between the effects of different surgical treatments and laboratory exams for schistosomal portal hypertension, especially concerning portal system thrombosis. The etiopathogenic factors of this thrombosis are not fully understood. In this study, the correlation between surgical treatment for schistosomal portal hypertension and the occurrence of postoperative portal system thrombosis was investigated. Methods: A total of 61 patients who underwent surgical treatment for schistosomal portal hypertension were distributed into four groups: Patients in Group 1 (n=12) underwent portal variceal disconnection associated with splenic artery ligation and spleen preservation. Patients in Group 2 (n=20) underwent portal variceal disconnection and total splenectomy. Patients in Group 3 (n=20) underwent portal variceal disconnection with subtotal splenectomy, preserving the upper splenic pole supplied by the splenogastric vessels. Patients in Group 4 (n=9) underwent portal variceal disconnection with total splenectomy and autogenous splenic implants on the greater omentum. Late postoperative portal vein thrombosis was diagnosed using Doppler ultrasound. Results: Over the 10-year follow-up, portal vein thrombosis occurred in 26 operated patients (42.6%), with no significant difference observed among the four surgical groups (p=0.217). Most of the thrombi only partially occluded the portal system veins. All the patients presented with a thrombus inside the portal vein. There was no difference in hematological and biochemical tests between groups with or without portal vein thrombosis. Conclusions: Portal vein thrombosis is often observed in the late postoperative period, irrespective of the surgical treatment employed, and is not associated with patient characteristics or any hematological and biochemical tests.
Databáze:	MEDLINE
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