QEEG indices in traumatic brain injury - insights from the CAPTAIN RTMS trial.

Autor: Olivia VR; Department of Neurosciences, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.; RoNeuro Institute for Neurological Research and Diagnostic, Cluj-Napoca, Romania., Chira D; RoNeuro Institute for Neurological Research and Diagnostic, Cluj-Napoca, Romania.; RoNeuro Institute for Neurological Research and Diagnostic, Cluj-Napoca, Romania., Chelaru VF; RoNeuro Institute for Neurological Research and Diagnostic, Cluj-Napoca, Romania.; Faculty of Medicine, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania., Diana CD; Department of Neurosciences, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.; RoNeuro Institute for Neurological Research and Diagnostic, Cluj-Napoca, Romania., Livia LP; Department of Neurosciences, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.; RoNeuro Institute for Neurological Research and Diagnostic, Cluj-Napoca, Romania.; Neurology Clinic, Cluj County Emergency Clinical Hospital, Cluj-Napoca, Romania., Buruiană AM; RoNeuro Institute for Neurological Research and Diagnostic, Cluj-Napoca, Romania., Mureşanu FD; Department of Neurosciences, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.; RoNeuro Institute for Neurological Research and Diagnostic, Cluj-Napoca, Romania.; Neurology Clinic, Cluj County Emergency Clinical Hospital, Cluj-Napoca, Romania.
Jazyk: angličtina
Zdroj: Journal of medicine and life [J Med Life] 2024 Mar; Vol. 17 (3), pp. 318-325.
DOI: 10.25122/jml-2024-0187
Abstrakt: This secondary analysis of the CAPTAIN-RTMS trial data focused on the significance of quantitative electroencephalography (qEEG) indices as indicators of recovery in patients with traumatic brain injury (TBI). By focusing on the delta alpha ratio (DAR), delta theta/alpha beta ratio (DTABR), and theta beta ratio (TBR), this study explored the shifts in brainwave activity as a response to an integrative treatment regimen of repetitive transcranial magnetic stimulation (rTMS) combined with the neurotrophic agent Cerebrolysin. Findings revealed significant increases in DAR and DTABR, suggesting changes in neurophysiological dynamics after treatment. However, variations in TBR were inconclusive in providing clear electrophysiological insights. These results indicate that further research is necessary to describe and understand the underlying mechanisms of brain recovery and to develop refined treatment frameworks for patients with TBI.
Competing Interests: The authors declare no conflict of interest.
(© 2024 by the authors.)
Databáze: MEDLINE
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