Endoscopic approach for biliopancreatic disease after pancreaticoduodenectomy: a 10-year single-center experience.

Autor: Capasso M; Gastroenterology and Endoscopy Department, ASST Maggiore Hospital, Largo Ugo Dossena 2, 26013, Crema (CR), Italy.; Department of Clinical Medicine and Surgery, Diseases of the Liver and Biliary System Unit, University 'Federico II', Via Sergio Pansini 5, 80131, Naples, Italy., Dioscoridi L; Digestive and Interventional Endoscopy Unit, Niguarda Hospital, Piazza Dell'Ospedale Maggiore 3, 20161, Milan, Italy. dioscoridi.lorenzo@virgilio.it.; Digestive and Interventional Endoscopy Unit, ASST Niguarda Hospital, Piazza Dell'Ospedale Maggiore 3, 20162, Milan, Italy. dioscoridi.lorenzo@virgilio.it., Forti E; Digestive and Interventional Endoscopy Unit, Niguarda Hospital, Piazza Dell'Ospedale Maggiore 3, 20161, Milan, Italy., Pugliese F; Digestive and Interventional Endoscopy Unit, Niguarda Hospital, Piazza Dell'Ospedale Maggiore 3, 20161, Milan, Italy., Cintolo M; Digestive and Interventional Endoscopy Unit, Niguarda Hospital, Piazza Dell'Ospedale Maggiore 3, 20161, Milan, Italy., Bonato G; Digestive and Interventional Endoscopy Unit, Niguarda Hospital, Piazza Dell'Ospedale Maggiore 3, 20161, Milan, Italy., Bravo M; Digestive and Interventional Endoscopy Unit, Niguarda Hospital, Piazza Dell'Ospedale Maggiore 3, 20161, Milan, Italy., Palermo A; Digestive and Interventional Endoscopy Unit, Niguarda Hospital, Piazza Dell'Ospedale Maggiore 3, 20161, Milan, Italy., Fimiano F; Digestive and Interventional Endoscopy Unit, Niguarda Hospital, Piazza Dell'Ospedale Maggiore 3, 20161, Milan, Italy., Mutignani M; Digestive and Interventional Endoscopy Unit, Niguarda Hospital, Piazza Dell'Ospedale Maggiore 3, 20161, Milan, Italy.
Jazyk: angličtina
Zdroj: Surgical endoscopy [Surg Endosc] 2024 Sep; Vol. 38 (9), pp. 5187-5198. Date of Electronic Publication: 2024 Jul 23.
DOI: 10.1007/s00464-024-11095-0
Abstrakt: Background and Aim: In surgically altered anatomy (SAA), endoscopic retrograde cholangiopancreatography (ERCP) can be challenging, and it remains debatable the choice of the optimal endoscopic approach within this context. We aim to show our experience and evaluate the technical and clinical success of endoscopic treatment performed in the setting of adverse events (AE) after pancreaticoduodenectomy (PD).
Methods: This study was conducted on a retrospective cohort of patients presenting biliopancreatic complications after PD from 01/01/2012 to 31/12/2022. All patients underwent ERCP at our Endoscopy Unit. Clinical, instrumental data, and characteristics of endoscopic treatments were collected.
Results: 133 patients were included (80 M, mean age = 65 y.o.) with a total of 296 endoscopic procedures (median = 2 procedures/treatment). The indications for ERCP were mainly biliary AE (76 cases, 57.1%). Technical success was obtained in 121 patients of 133 (90.9%). 112 out of 133 (84.2%) obtained clinical success. Nine patients out of 112 (8%) experienced AEs. Clinical success rates were statistically different between patients with biliary or pancreatic disease (93.4% vs 73.6%, p < 0.0001). Septic patients were 38 (28.6%) and showed a worse prognosis than non-septic ones (clinical success: 65.7% vs 91.5%, p = 0.0001). During follow-up, 9 patients (8%), experienced recurrence of the index biliopancreatic disease with a median onset at 20 months (IQR 6-40.1).
Conclusion: Our case series demonstrated that the use of a pediatric colonoscope in ERCP procedures for patients with AEs after PD is both safe and effective in treating the condition, even in a long-term follow-up.
(© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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