Recurring Transient Tooth Pain as Newly Described Symptom of Migratory Loiasis: A Mixed-Methods Study in Rural Gabon.

Autor:	Hildebrandt TR; Centre de Recherches Médicales de Lambaréné, Lambarene, Gabon.; Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine and I. Department of Medicine University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Ramharter H; Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine and I. Department of Medicine University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Lumeka Kabwende A; Centre de Recherches Médicales de Lambaréné, Lambarene, Gabon., Endamne L; Centre de Recherches Médicales de Lambaréné, Lambarene, Gabon.; Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine and I. Department of Medicine University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Davi SD; Centre de Recherches Médicales de Lambaréné, Lambarene, Gabon.; Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine and I. Department of Medicine University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Adegnika AA; Centre de Recherches Médicales de Lambaréné, Lambarene, Gabon.; Institute for Tropical Medicine, University of Tübingen, Tübingen, Germany., Mombo-Ngoma G; Centre de Recherches Médicales de Lambaréné, Lambarene, Gabon.; Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine and I. Department of Medicine University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Agnandji ST; Centre de Recherches Médicales de Lambaréné, Lambarene, Gabon., Mischlinger J; Centre de Recherches Médicales de Lambaréné, Lambarene, Gabon.; Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine and I. Department of Medicine University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; German Center for Infection Research, Partner Site Hamburg-Lübeck-Borstel-Riems, Germany., Manego Zoleko R; Centre de Recherches Médicales de Lambaréné, Lambarene, Gabon.; Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine and I. Department of Medicine University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Ramharter M; Centre de Recherches Médicales de Lambaréné, Lambarene, Gabon.; Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine and I. Department of Medicine University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; German Center for Infection Research, Partner Site Hamburg-Lübeck-Borstel-Riems, Germany.
Jazyk:	angličtina
Zdroj:	The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2024 Jul 23; Vol. 111 (4), pp. 826-828. Date of Electronic Publication: 2024 Jul 23 (Print Publication: 2024).
DOI:	10.4269/ajtmh.24-0059
Abstrakt:	Loiasis, a filarial pathogen exclusively endemic in central and western Africa, causes a wide spectrum of symptoms. Understanding the breadth of its clinical manifestations is of importance for adequate patient care and to understand its disease burden. Recurring transient pain in the oral cavity was reported as a self-perceived symptom of loiasis in in-depth interviews of patients in a high transmission region in Gabon. Pain was described as stabbing in character and transient for a few days in its temporal course. A quantitative epidemiological survey indicated that transient tooth pain was experienced by 22% of patients infected with Loa loa. Among those individuals, it was exclusively reported by patients suffering from migratory loiasis (24%). Similar findings have been previously described for other filarial pathogens, indicating that transient swellings of the periodontium and the soft tissue of the oral cavity may explain this symptom reported by patients with migratory loiasis.
Databáze:	MEDLINE
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