A case report of de novo histoid leprosy in a Nigerian male: A diagnostic dilemma.

Autor:	Anaje CC; Department of Internal Medicine, NAUTH, Nnewi, Anambra State, Nigeria., Okpala CI; Department of Internal Medicine, NAUTH, Nnewi, Anambra State, Nigeria., Enechukwu NA; Department of Internal Medicine, NAUTH, Nnewi, Anambra State, Nigeria., Menkiti FE; Department of Histopathology, NAUTH, Nnewi, Anambra State, Nigeria., Ezejiofor IF; Department of Histopathology, NAUTH, Nnewi, Anambra State, Nigeria., Umenzekwe CC; Department of Internal Medicine, NAUTH, Nnewi, Anambra State, Nigeria.
Jazyk:	angličtina
Zdroj:	Tropical doctor [Trop Doct] 2024 Oct; Vol. 54 (4), pp. 380-382. Date of Electronic Publication: 2024 Jul 23.
DOI:	10.1177/00494755241263615
Abstrakt:	Histoid leprosy is an uncommon variant of lepromatous leprosy. It poses a diagnostic challenge because of its distinctive clinical and histopathological features. It presents as smooth papules and nodules that rarely ulcerate. We present the case of a 22-year-old Nigerian man with a 2-year history of multiple, dome-shaped papules and nodules on the skin with necrotic centres. General examination showed right axillary lymphadenopathy, non-pitting oedema, foot ulcer, and glove and stocking sensation loss. Despite previous misdiagnoses, histopathological examination showed dermal expansion by histiocytes arranged in a storiform pattern. Slit skin smear yielded abundant bacilli. The patient was started on WHO multidrug treatment, resulting in the improvement of his lesions. This case emphasises the importance of increased awareness of this rare presentation of leprosy. Competing Interests: Declaration of conflicting interestsThe authors declared no potential conflicts of interest with respect to the research, authorship and/or publication of this article.
Databáze:	MEDLINE
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