Prognostic value of serum albumin in heart failure patients with cardiac resynchronization therapy.

Autor: Pay L; Department of Cardiology, Ardahan State Hospital, 75000, Ardahan, Turkey., Yumurtaş AÇ; Department of Cardiology, Kars Harakani State Hospital, 36200, Kars, Turkey., Tezen O; Department of Cardiology, Bayrampasa State Hospital, 34040, Istanbul, Turkey., Çetin T; Department of Cardiology, Dr Siyami Ersek Thoracic & Cardiovascular Surgery Training Hospital, 34668, Istanbul, Turkey., Eren S; Department of Cardiology, Dr Siyami Ersek Thoracic & Cardiovascular Surgery Training Hospital, 34668, Istanbul, Turkey., Çınar T; Department of Medicine, University of Maryland Medical Center Midtown Campus, MD 21201, USA., Hayıroğlu Mİ; Department of Cardiology, Dr Siyami Ersek Thoracic & Cardiovascular Surgery Training Hospital, 34668, Istanbul, Turkey.
Jazyk: angličtina
Zdroj: Biomarkers in medicine [Biomark Med] 2024; Vol. 18 (8), pp. 363-371. Date of Electronic Publication: 2024 May 24.
DOI: 10.1080/17520363.2024.2347200
Abstrakt: Aim: There is a lack of data about the association between admission serum albumin levels and long-term mortality in heart failure (HF) patients with cardiac resynchronization therapy defibrillators (CRT-D). We aim to investigate this connection in HF patients with CRT-D. Methods: The study population consisted of 477 HF patients with CRT-D. The cohort was divided into three groups according to albumin values, and the relationship between these groups and long-term mortality were evaluated. Results: Long-term all-cause mortality (HR: 3.32, 95% CI: 2.12-6.84), appropriate (HR: 4.44, 95% CI: 2.44-8.06) and inappropriate (HR: 2.95, 95% CI: 1.88-6.02) shocks were higher in the low albumin group. Conclusion: Low albumin levels are associated with the long-term mortality and appropriate shock treatment in HF patients with CRT-D.
Databáze: MEDLINE