Wits Transplant Unit Annual Report 2022: Adult and paediatric liver transplantation.

Autor:	Wessels EU; Wits Donald Gordon Medical Centre, University of the Witwatersrand, Johannesburg, South Africa. eu.wessels@gmail.com., Kinandu K; Wits Donald Gordon Medical Centre, University of the Witwatersrand, Johannesburg, South Africa. kkamauu@yahoo.co.uk., Beretta M; Wits Donald Gordon Medical Centre, University of the Witwatersrand, Johannesburg, South Africa. rees.beretta@gmail.com., Berkenfeld S; Wits Donald Gordon Medical Centre, University of the Witwatersrand, Johannesburg, South Africa; . sberkenfeld@gmail.com., Bobat B; Wits Donald Gordon Medical Centre, University of the Witwatersrand, Johannesburg, South Africa; Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. bilalbobat@mweb.co.za., Brannigan L; Wits Donald Gordon Medical Centre, University of the Witwatersrand, Johannesburg, South Africa. lliambrannigan@yahoo.com., Britz R; Wits Donald Gordon Medical Centre, University of the Witwatersrand, Johannesburg, South Africa; Department of Surgery, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. rsbritz@gmail.com., Demopoulos D; Wits Donald Gordon Medical Centre, University of the Witwatersrand, Johannesburg, South Africa. docdespina@yahoo.com., Doedens L; Wits Donald Gordon Medical Centre, University of the Witwatersrand, Johannesburg, South Africa. linda.doedens@wits.ac.za., Gaylard P; Data Management and Statistical Analysis (DMSA), Johannesburg, South Africa. petra@dmsa.co.za., Maher H; Wits Donald Gordon Medical Centre, University of the Witwatersrand, Johannesburg, South Africa. heathermaher@mweb.co.za., Mahomed A; Wits Donald Gordon Medical Centre, University of the Witwatersrand, Johannesburg, South Africa; Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. Adam.Mahomed@wits.ac.za., Mudau V; Wits Donald Gordon Medical Centre, University of the Witwatersrand, Johannesburg, South Africa. vusanimudau@icloud.com., Parbhoo D; Wits Donald Gordon Medical Centre, University of the Witwatersrand, Johannesburg, South Africa. dinenparbhoo@gmail.com., Rambarran S; Wits Donald Gordon Medical Centre, University of the Witwatersrand, Johannesburg, South Africa. sharan.rambarran@gmail.com., Reynders M; Wits Donald Gordon Medical Centre, University of the Witwatersrand, Johannesburg, South Africa. marelizereynders@outlook.com., Van der Schyff F; Wits Donald Gordon Medical Centre, University of the Witwatersrand, Johannesburg, South Africa. francisca.vds@gmail.com., Ströbele B; Wits Donald Gordon Medical Centre, University of the Witwatersrand, Johannesburg, South Africa. bstr@proton.me., Fabian J; Wits Donald Gordon Medical Centre, University of the Witwatersrand, Johannesburg, South Africa; Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. june.fabian@mweb.co.za., Loveland J; Wits Donald Gordon Medical Centre, University of the Witwatersrand, Johannesburg, South Africa; Department of Surgery, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. jeromeloveland@icloud.com.
Jazyk:	angličtina
Zdroj:	South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde [S Afr Med J] 2024 Apr 24; Vol. 114 (3b), pp. e1365. Date of Electronic Publication: 2024 Apr 24.
DOI:	10.7196/SAMJ.2024.v114i3b.1365
Abstrakt:	In 2022, the Wits Transplant Unit performed 57 liver transplants: 33/57 adult (58%) and 24/57 paediatric (42%) recipients. At the beginning of 2022, 28 candidates were on the adult waitlist. Forty-six candidates were added to the waitlist during the year. Sixty-five percent of waitlisted candidate were transplanted. Adult candidates remained on the waitlist for longer than previous years, with 52% of them waitlisted for less than one year before undergoing liver transplantation. There was a decrease in adult pretransplant mortality to 9% in 2021 from 25% in 2020. The most common aetiology in waitlist candidates was alcoholic steatohepatitis (ASH)/non-alcoholic steatohepatitis (NASH) (36%) and in recipients cholestatic (primary sclerosing cholangitis (PSC) and primary biliary sclerosis (PBC)) (40%). Most adult recipients received a deceased donor graft (79%). Unadjusted recipient one- and three-year survivals were 75% (95% confidence interval (CI) 65 - 83) and 74% (95% CI 65 - 81), respectively. In the paediatric population, the most common aetiologies for both pretransplant candidates and transplant recipients remained cholestatic disease and acute liver failure. There was a decrease in paediatric pretransplant mortality from 27% in 2017 to 6% in 2021. Unlike the adult cohort, most paediatric recipients received a living donor graft (79%). Unadjusted one-year and three-year survival rates were 85% (95% CI 75 - 92) and 68% (95% CI 56 - 77), respectively.
Databáze:	MEDLINE
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