Ct-based diagnosis of sarcopenia as a prognostic factor for postoperative mortality after elective open-heart surgery in older patients: a cohort-based systematic review and meta-analysis.

Autor:	Yang TR; Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.; The Research Units of West China (2018RU012)-Chinese Academy of Medical Sciences, West China Hospital, Sichuan University, Chengdu, Sichuan, China., Ji P; Department of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China., Deng X; Department of Anesthesiology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.; Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, Sichuan University, Chengdu, Sichuan, China., Feng XX; Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.; The Research Units of West China (2018RU012)-Chinese Academy of Medical Sciences, West China Hospital, Sichuan University, Chengdu, Sichuan, China., He ML; Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.; The Research Units of West China (2018RU012)-Chinese Academy of Medical Sciences, West China Hospital, Sichuan University, Chengdu, Sichuan, China., Wang RR; Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.; The Research Units of West China (2018RU012)-Chinese Academy of Medical Sciences, West China Hospital, Sichuan University, Chengdu, Sichuan, China.; Department of Anesthesiology, Chengdu Shang Jin Nan Fu Hospital/Shang Jin Hospital of West China Hospital, Sichuan University, Chengdu, Sichuan, China., Li XH; Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.; The Research Units of West China (2018RU012)-Chinese Academy of Medical Sciences, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Jazyk:	angličtina
Zdroj:	Frontiers in public health [Front Public Health] 2024 Jul 08; Vol. 12, pp. 1378462. Date of Electronic Publication: 2024 Jul 08 (Print Publication: 2024).
DOI:	10.3389/fpubh.2024.1378462
Abstrakt:	Background: Cardiac open-heart surgery, which usually involves thoracotomy and cardiopulmonary bypass, is associated with a high incidence of postoperative mortality and adverse events. In recent years, sarcopenia, as a common condition in older patients, has been associated with an increased incidence of adverse prognosis. Methods: We conducted a search of databases including PubMed, Embase, and Cochrane, with the search date up to January 1, 2024, to identify all studies related to elective cardiac open-heart surgery in older patients. We used the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach to assess the certainty of evidence. Results: A total of 12 cohort studies were included in this meta-analysis for analysis. This meta-analysis revealed that patients with sarcopenia had a higher risk of postoperative mortality. Furthermore, the total length of hospital stay and ICU stay were longer after surgery. Moreover, there was a higher number of patients requiring further healthcare after discharge. Regarding postoperative complications, sarcopenia patients had an increased risk of developing renal failure and stroke. Conclusion: Sarcopenia served as a tool to identify high-risk older patients undergoing elective cardiac open-heart surgery. By identifying this risk factor early on, healthcare professionals took targeted steps to improve perioperative function and made informed clinical decisions. Systematic review registration : https://www.crd.york.ac.uk/prospero/, identifier CRD42023426026. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2024 Yang, Ji, Deng, Feng, He, Wang and Li.)
Databáze:	MEDLINE
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