The Epidemiology of Pediatric Thermal Injury-Associated Toxic Shock Syndrome: A Systematic Review.

Autor: Alrasheed MF; College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia., Alkhalaf H; College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center, King Abdulaziz Medical City, Riyadh, Saudi Arabia.; Department of Pediatrics, King Abdullah Specialist Children's Hospital, Riyadh, Saudi Arabia., Alqahtani AM; College of medicine, Imam Mohammad Ibn Saud University, Riyadh, Saudi Arabia., Alzubaidi AS; Department of Pediatrics, Prince Meshari Bin Saud Hospital, Albaha, Saudi Arabia., Alasmari AA; Department of Forensic Medicine, Forensic Medicine Center, Jeddah, Saudi Arabia., Al-Osimi DO; Department of Pediatrics, Al Hada Armed Forces Hospital, Taif, Saudi Arabia., Bahkali LH; Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Alholais AM; Collage of medicine, Taif University, Taif, Saudi Arabia., Basheikh NI; Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Althaqafi AM; Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Almousa NM; College of health and Rehabilitation science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia., Al Mazrou FH; College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia., Alsadiq AA; Department of primary healthcare, Abqaiq general hospital, Abqaiq, Saudi Arabia., Kazzaz YM; College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.; King Abdullah International Medical Research Center, King Abdulaziz Medical City, Riyadh, Saudi Arabia.; Department of Pediatrics, King Abdullah Specialist Children's Hospital, Riyadh, Saudi Arabia.
Jazyk: angličtina
Zdroj: Journal of burn care & research : official publication of the American Burn Association [J Burn Care Res] 2024 Jul 23. Date of Electronic Publication: 2024 Jul 23.
DOI: 10.1093/jbcr/irae141
Abstrakt: Thermal injury-associated toxic shock syndrome (TSS) is a life-threatening condition that can occur in children following burn injuries. The objective of this study was to describe the clinical manifestations, treatment, and outcomes of children who experienced TSS following a thermal injury. Additionally, the existing literature was systematically examined, and published cases of pediatric TSS occurring after burns were compiled. In June 2023, without regard for time constraints, articles that met the criteria were searched across several electronic databases. The inclusion criteria were English-language publications, pediatric patients, and reported outcomes of interest for clinical questions. Due to the heterogeneity of the included publications and the lack of data in an appropriate format, a meta-analysis was not feasible. Our research identified 23 studies published between 1980 and 2023, including 72 cases (from multiple countries) that met the inclusion criteria. Of the 72 patients with thermal injuries complicated by TSS, 53 (73.6%) children survived, 6 (8.3%) died, and for 13 (18%) cases, the outcome was not documented. Our systematic review highlights the rarity, severity, and complexity of pediatric thermal injury-associated TSS. Key findings from the review indicate that pediatric thermal injury-associated TSS carries a high mortality rate and significant morbidity. By increasing awareness, improving diagnostic accuracy, and optimizing treatment strategies, healthcare professionals can improve patient outcomes in this challenging condition.
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Databáze: MEDLINE