| Autor: |
Tian CY; School of Basic Medicine and Forensic Medicine, Baotou Medical College, Baotou 014040, China., Yang QR; School of Pharmacy, Baotou Medical College, Baotou 014040, China., Fan LX; School of Pharmacy, Baotou Medical College, Baotou 014040, China., Yang YM; School of Pharmacy, Baotou Medical College, Baotou 014040, China., Gao BW; School of Pharmacy, Baotou Medical College, Baotou 014040, China., Yang JB; Institute for Control of Chinese Traditional Medicine and Ethnic Medicine, National Institutes for Food and Drug Control, Beijing 100050, China. |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of Asian natural products research [J Asian Nat Prod Res] 2024 Jul 22, pp. 1-15. Date of Electronic Publication: 2024 Jul 22. |
| DOI: |
10.1080/10286020.2024.2379981 |
| Abstrakt: |
Zhachong-13 pills (ZC-13), as a traditional prescription of Mongolian medicine, are often used in the clinical practice of Mongolian hospitals for the treatment of stroke and rheumatic arthritis. In this experiment, UHPLC-Q-Exactive Orbitrap MS was used to explore the chemical composition of ZC-13. The results showed that 315 compounds were identified or inferred, including 56 alkaloids, 77 2-(2-phenylethyl)chromones, 61 flavonoids, 31 tannins, 8 coumarins, 16 lignans, 21 terpenoids, 5 amino acids, 19 organic acids, and 21 other components. In addition, the pharmacological activities related to anti-cerebral ischemia of these components were summarized. This result laid a foundation for further study on the pharmacodynamic material basis of ZC-13 and provided a scientific basis for the formulation of ZC-13 quality specifications. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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