Sensitivity and specificity of the action observation network to kinematics, target object, and gesture meaning.

Autor: Simonelli F; IMT School for Advanced Studies Lucca, Lucca, Italy., Handjaras G; IMT School for Advanced Studies Lucca, Lucca, Italy., Benuzzi F; Department of Biomedical, Metabolic and Neural Sciences and Center for Neuroscience and Neurotechnology, University of Modena and Reggio Emilia, Modena, Italy., Bernardi G; IMT School for Advanced Studies Lucca, Lucca, Italy., Leo A; IMT School for Advanced Studies Lucca, Lucca, Italy., Duzzi D; Department of Biomedical, Metabolic and Neural Sciences and Center for Neuroscience and Neurotechnology, University of Modena and Reggio Emilia, Modena, Italy., Cecchetti L; IMT School for Advanced Studies Lucca, Lucca, Italy., Nichelli PF; Department of Biomedical, Metabolic and Neural Sciences and Center for Neuroscience and Neurotechnology, University of Modena and Reggio Emilia, Modena, Italy., Porro CA; Department of Biomedical, Metabolic and Neural Sciences and Center for Neuroscience and Neurotechnology, University of Modena and Reggio Emilia, Modena, Italy., Pietrini P; IMT School for Advanced Studies Lucca, Lucca, Italy., Ricciardi E; IMT School for Advanced Studies Lucca, Lucca, Italy., Lui F; Department of Biomedical, Metabolic and Neural Sciences and Center for Neuroscience and Neurotechnology, University of Modena and Reggio Emilia, Modena, Italy.
Jazyk: angličtina
Zdroj: Human brain mapping [Hum Brain Mapp] 2024 Aug 01; Vol. 45 (11), pp. e26762.
DOI: 10.1002/hbm.26762
Abstrakt: Hierarchical models have been proposed to explain how the brain encodes actions, whereby different areas represent different features, such as gesture kinematics, target object, action goal, and meaning. The visual processing of action-related information is distributed over a well-known network of brain regions spanning separate anatomical areas, attuned to specific stimulus properties, and referred to as action observation network (AON). To determine the brain organization of these features, we measured representational geometries during the observation of a large set of transitive and intransitive gestures in two independent functional magnetic resonance imaging experiments. We provided evidence for a partial dissociation between kinematics, object characteristics, and action meaning in the occipito-parietal, ventro-temporal, and lateral occipito-temporal cortex, respectively. Importantly, most of the AON showed low specificity to all the explored features, and representational spaces sharing similar information content were spread across the cortex without being anatomically adjacent. Overall, our results support the notion that the AON relies on overlapping and distributed coding and may act as a unique representational space instead of mapping features in a modular and segregated manner.
(© 2024 The Author(s). Human Brain Mapping published by Wiley Periodicals LLC.)
Databáze: MEDLINE
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