Unveiling the Rarity: A Case Report of Malignant Melanoma of the Rectum.

Autor:	Thatipalli N; General Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research, Wardha, IND., Tote D; General Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research, Wardha, IND., Zade A; General Surgery, Mahatma Gandhi Institute of Medical Sciences, Wardha, IND., Dahmiwal T; General Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research, Wardha, IND., Naseri S; Pathology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research, Wardha, IND.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Jun 20; Vol. 16 (6), pp. e62747. Date of Electronic Publication: 2024 Jun 20 (Print Publication: 2024).
DOI:	10.7759/cureus.62747
Abstrakt:	Malignant melanoma of the rectum is an aggressive malignant tumor with anal pain and rectal bleeding as common clinical symptoms with a low incidence. Intestinal metastases are a common form of cutaneous melanoma. On a cellular level, the fibrous stroma is observed to be in the form of compact nests with a signet ring-like appearance. This is a case of a 67-year-old male with major complaints of altered bowel habits, a history of rectal bleeding for four months, and pain during defecation. Upon digital rectal examination, nearly half of the anal lumen was occupied by a fleshy mass. A detailed examination showed an ulcerating, black-colored nodule extending from the anorectal junction. Imaging studies confirmed a polypoidal lesion in the distal rectum. Histopathological examination of the biopsies revealed features consistent with malignant melanoma, supported by positive staining for HMB-45 and S-100 markers. The patient underwent an open abdominoperineal resection, followed by postoperative management and the initiation of chemotherapy. This case can be noted as underscoring the criticality of the diagnosis and treatment of rectal malignant melanoma and highlighting the importance of early recognition for improved patient outcomes. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Thatipalli et al.)
Databáze:	MEDLINE
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