Isolated Self-Limited Right Oculomotor Nerve Palsy With Positive Asialo-GM1 Antibody After SARS-CoV-2 mRNA Vaccination.

Autor:	Ozobu I; Neurology, Adventist Health White Memorial, Los Angeles, USA., Salter E; Neurology, Adventist Health White Memorial, Los Angeles, USA., Salter S; Neurology, Adventist Health White Memorial, Los Angeles, USA., Peng D; Neurology, Adventist Health White Memorial, Los Angeles, USA., Sherbaf A; Internal Medicine, Adventist Health White Memorial, Los Angeles, USA., Ravinutala A; Internal Medicine, Adventist Health White Memorial, Los Angeles, USA., Liu AK; Neurology, Adventist Health White Memorial, Los Angeles, USA.; Neurology, Loma Linda University School of Medicine, Loma Linda, USA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Jul 21; Vol. 16 (7), pp. e65045. Date of Electronic Publication: 2024 Jul 21 (Print Publication: 2024).
DOI:	10.7759/cureus.65045
Abstrakt:	mRNA vaccines have been a critical tool in combating the current coronavirus disease 2019 (COVID-19) pandemic and demonstrated a high safety profile. However, rare cases of isolated oculomotor nerve palsy following vaccination have been reported. These few reported cases can be divided into two groups based on symptom onset: immediate and delayed. While most reported cases involving Pfizer and Moderna vaccines occurred within the first few days of vaccination, a few cases with delayed onset have also been described. We present a unique case of a patient experiencing isolated, unilateral oculomotor nerve palsy 14 days after receiving a Moderna booster shot. Notably, our case and a previously reported case of 17-day onset case share the interesting finding of positive ganglioside antibodies. This not only highlights the potential for unusual occurrences following COVID-19 vaccination but also opens up avenues for exploring the underlying mechanisms behind these events. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Adventist Health IRB issued approval N/A. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Ozobu et al.)
Databáze:	MEDLINE
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