Association of Mean Platelet Volume with Grades of Hypertensive Retinopathy.

Autor: Keyal S; Department of Gastroenterology, Amrita Institute of Medical Science, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India., Vasant PK; Department of General Medicine, Amrita Institute of Medical Science, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India., Kulirankal KG; Department of General Medicine, Amrita Institute of Medical Science, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
Jazyk: French; English
Zdroj: Annals of African medicine [Ann Afr Med] 2024 Jul 01; Vol. 23 (3), pp. 488-493. Date of Electronic Publication: 2024 Apr 04.
DOI: 10.4103/aam.aam_130_23
Abstrakt: Objective: Hypertension is the most prevalent non communicable disease causing deaths even before evidence of target organ damage. Platelet activation is associated with risk of vascular events. Identification of mean platelet volume (MPV) values in patients with hypertensive retinopathy (HR) can help in prognostication and risk stratification of possible complications.
Materials and Methods: Patients presenting to the outpatient department over a period of 18 months underwent clinical examination, blood sampling, direct ophthalmoscopic examination, and two-dimensional echocardiography.
Results: Out of 104 subjects, there were a total of 25 females and 79 males. Patients with grade 1HR had a mean MPV value of 9.4, those with grade 2 HR had a mean MPV of 9.8, among people with grade 3 HR the mean MPV was 10.1, and those with grade 4 HR had a mean MPV of 10.9.
Conclusion: In our study, we have seen that MPV increases with increasing severity of HR, thus implying that MPV probably plays a role in HR. Testing of MPV can be used to decide whether preventative treatments should be instituted to the prevent the severe complications of retinopathy and thus decrease the risk and occurrence of cardiovascular and cerebrovascular events.
(Copyright © 2024 Copyright: © 2024 Annals of African Medicine.)
Databáze: MEDLINE
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