Helicobacter pylori-Associated Immune Thrombocytopenia: Diagnostic and Therapeutic Approach.

Autor: Gosavi S; Department of Internal Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka., Krishnan G; Department of Internal Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka., Kumar V; Department of Internal Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka., Nityandila CA; Healseq Precision Medicine Private Limited, Indian Institute of Science, Bengaluru, Karnataka., Rao AA; Department of Biological Sciences, Mellon College of Science, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA., Singh S; Department of Emergency Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand., Shastry BAK; Department of Internal Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka.
Jazyk: French; English
Zdroj: Annals of African medicine [Ann Afr Med] 2024 Jul 01; Vol. 23 (3), pp. 248-254. Date of Electronic Publication: 2024 Mar 11.
DOI: 10.4103/aam.aam_170_23
Abstrakt: The relationship between immune thrombocytopenia (ITP) and Helicobacterpylori infection has largely been an unexplored entity. This review article aims at focusing on the role of H. pylori in secondary ITP. We also elucidated the importance of diagnostic workup and treatment of H. pylori in this article. The mechanisms of H. pylori-associated ITP have been covered in this article. The factors determining platelet response to H. pylori eradication therapy have been mentioned. It is extremely crucial to be aware that H. pylori is a major causative pathogen for new-onset ITP as well as chronic ITP. Upper gastrointestinal endoscopic biopsy is the best invasive method for the diagnosis of the same. Further studies need to be conducted across larger, more diverse groups to validate our observation that eradication of H. pylori could aid platelet recovery in ITP.
(Copyright © 2024 Copyright: © 2024 Annals of African Medicine.)
Databáze: MEDLINE
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