The complete genome of equid herpesvirus-1 (EHV-1) field isolates from Argentina reveals an interspecific recombinant strain.

Autor: Tau RL; Institute of Virology and Technological Innovations, Dr Nicolas Repetto and De losReseros, IVIT (INTA-CONICET), 1686, Hurlingham, Buenos Aires, Argentina., Marandino AE; Evolutionary Genetics Section, Faculty of Sciences, Institute of Biology, University of the Republic, Montevideo, Uruguay., Panzera Y; Evolutionary Genetics Section, Faculty of Sciences, Institute of Biology, University of the Republic, Montevideo, Uruguay., Alamos F; Institute of Virology and Technological Innovations, Dr Nicolas Repetto and De losReseros, IVIT (INTA-CONICET), 1686, Hurlingham, Buenos Aires, Argentina.; Faculty of Agricultural and Veterinary Sciences, Veterinary Research Institute, University of the Salvador, Buenos Aires, Argentina., Vissani MA; Institute of Virology and Technological Innovations, Dr Nicolas Repetto and De losReseros, IVIT (INTA-CONICET), 1686, Hurlingham, Buenos Aires, Argentina.; Faculty of Agricultural and Veterinary Sciences, Veterinary Research Institute, University of the Salvador, Buenos Aires, Argentina., Romera SA; Institute of Virology and Technological Innovations, Dr Nicolas Repetto and De losReseros, IVIT (INTA-CONICET), 1686, Hurlingham, Buenos Aires, Argentina.; Faculty of Agricultural and Veterinary Sciences, Veterinary Research Institute, University of the Salvador, Buenos Aires, Argentina., Pérez R; Evolutionary Genetics Section, Faculty of Sciences, Institute of Biology, University of the Republic, Montevideo, Uruguay., Maidana SS; Institute of Virology and Technological Innovations, Dr Nicolas Repetto and De losReseros, IVIT (INTA-CONICET), 1686, Hurlingham, Buenos Aires, Argentina. maidana.silvina@inta.gob.ar.; Faculty of Agricultural and Veterinary Sciences, Veterinary Research Institute, University of the Salvador, Buenos Aires, Argentina. maidana.silvina@inta.gob.ar.
Jazyk: angličtina
Zdroj: Virus genes [Virus Genes] 2024 Oct; Vol. 60 (5), pp. 559-562. Date of Electronic Publication: 2024 Jul 19.
DOI: 10.1007/s11262-024-02093-4
Abstrakt: The Equid alphaherpesvirus type 1 (EHV-1) infection can have devastating economic consequences in the horse industry due to large-scale outbreaks of abortions, perinatal foal mortality, and myeloencephalopathy. The present study analyzed the genome of two isolates obtained from aborted fetuses in Argentina, E/745/99 and E/1297/07. The E745/99 genome shares 98.2% sequence identity with Ab4, a reference EHV-1 strain. The E/1297/07 genome shares 99.8% identity with NY03, a recombinant strain containing part of ORF64 and part of the intergenic region from Equid alphaherpesvirus-4 (EHV-4). The E/1297/07 genome has the same breakpoints as other United States and Japanese recombinants, including NY03. The recombinant regions have varying numbers of tandem repeat sequences and different minor parental sequences (EHV-4), suggesting distinct origins of the recombinant events. These are the first complete genomes of EHV-1 from Argentina and South America available in the Databases.
(© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
Externí odkaz: