Anabolic treatment for osteoporosis and fragility fracture risk: one year in review 2024.

Autor: De Mattia G; Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy. dr.g.demattia@gmail.com., Maffi M; Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy., Mazzantini M; Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
Jazyk: angličtina
Zdroj: Clinical and experimental rheumatology [Clin Exp Rheumatol] 2024 Jul; Vol. 42 (7), pp. 1311-1316. Date of Electronic Publication: 2024 Jul 18.
DOI: 10.55563/clinexprheumatol/7f52vl
Abstrakt: Osteoporosis is a skeletal disease characterised by reduced bone mass and deterioration of bone microarchitecture, underlying a higher risk of fragility fractures. Several options are available for its treatment, including both anti-resorptive and anabolic agents. The present review discusses and summarises the most recent literature on anabolic treatment, with a focus on abaloparatide, and on the assessment of fragility fracture risk, with a focus on trabecular bone score. Finally, we provide a discussion on the effects of different antiosteoporotic medications in terms of fragility fracture risk reduction.
Databáze: MEDLINE