Frailty and socioeconomic position: A systematic review of observational studies.

Autor: Hanlon P; School of Health and Wellbeing, University of Glasgow, UK. Electronic address: Peter.hanlon@glasgow.ac.uk., Politis M; School of Health and Wellbeing, University of Glasgow, UK., Wightman H; School of Health and Wellbeing, University of Glasgow, UK., Kirkpatrick S; School of Health and Wellbeing, University of Glasgow, UK., Jones C; School of Health and Wellbeing, University of Glasgow, UK., Khan M; School of Health and Wellbeing, University of Glasgow, UK., Bezzina C; School of Health and Wellbeing, University of Glasgow, UK., Mackinnon S; School of Health and Wellbeing, University of Glasgow, UK., Rennison H; School of Health and Wellbeing, University of Glasgow, UK., Wei L; School of Health and Wellbeing, University of Glasgow, UK., Vetrano DL; Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Tomtebodavägen 18 A, floors 9 and 10, Solna, Sweden; Stockholm Gerontology Research Center, Sveavägen 155, Stockholm, Sweden., Blane DN; School of Health and Wellbeing, University of Glasgow, UK., Dent E; Caring Futures Institute, College of Nursing and Health Sciences, Flinders University, Adelaide, SA, Australia; Adelaide Primary Health Network, Adelaide, SA, Australia., Hoogendijk EO; Department of Epidemiology & Data Science, Amsterdam UMC - Location VU University Medical Center, Amsterdam, the Netherlands.
Jazyk: angličtina
Zdroj: Ageing research reviews [Ageing Res Rev] 2024 Sep; Vol. 100, pp. 102420. Date of Electronic Publication: 2024 Jul 16.
DOI: 10.1016/j.arr.2024.102420
Abstrakt: Background: Frailty, an age-related state of reduced physiological reserve, is often associated with lower socio-economic position (SEP). This systematic review synthesised observational studies assessing (i) the association between SEP and frailty prevalence; (ii) how changes in frailty status over time vary by SEP; and (iii) whether the association between frailty and clinical outcomes is modified by SEP.
Methods: We searched three electronic databases from 2001 to 2023. We included observational studies measuring early-, mid-, and late-life indicators of SEP (education, income, wealth, housing, occupation, and area-based measures of multiple deprivation) and frailty (assessed using any validated measure). Screening and extraction were performed in duplicate. Findings were synthesised using narrative synthesis.
Results: We included 383 studies reporting findings from 265 independent samples/cohorts across 64 countries. Lower SEP was associated with higher frailty prevalence across all indicators (childhood deprivation 7/8 studies, education 227/248, occupation 28/32, housing 8/9, income 98/108, wealth 39/44 and area-based deprivation 32/34). Lower SEP was also associated with higher frailty incidence (27/30), with greater odds of transitioning towards a more severe frailty state (35/43), lower odds of frailty reversion (7/11), and (in some studies) with more rapid accumulation of deficits (7/15). The relationship between frailty and mortality was not modified by SEP.
Interpretation: Preventative measures across multiple levels of individual and structural inequality are likely to be required to reduce the rising levels of frailty. Resourcing of interventions and services to support people living with frailty should be proportionate to needs in the population to avoid widening existing health inequalities.
Competing Interests: Declaration of Competing Interest The authors declare no competing interests.
(Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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